Dontshootrude

Do you process your own firewood? Where do you source your wood, and how big is your log splitter? How long does it take to accumulate 10 cords of wood?

Are you sure you had an antibody test? The way you are describing things is a bit vague. If you are vaxxed you should be IgG positive for Spike (S). If you also recovered from infection then you will also be IgG positive for N (nucleocapsid). If you were vaxxed only then the N antibody test was positive. Remember that PCR and in home tests won't give you an antibody status as they are detecting the pathogen directly, and are not measuring your immune response.

Good news for those of you that had breakthrough infections: https://www.science.org/doi/10.1126/sciimmunol.abn8014

The common cold is caused by a number of viruses. There are 4 coronaviruses that circulate, but in my experience rhinoviruses and adenoviruses are more prevalent.

Omicron significantly evades antibody responses both from vaccination and infection with prior variants, but the T cell responses still offer good protection from serious illness. Recovery from the virus should provide a broader range of T cell responses compared to vaccination.

https://www.google.com/amp/s/www.nytimes.com/live/2022/01/03/technology/elizabeth-holmes-trial-verdict.amp.html Guilty of wire fraud totaling more than $140 million. That's going to sting.

Agree with this. I use semolina in my ooni and it comes out great. Parchment paper use less than ideal in an ooni where your pizza cooks in a minute.

Exactly. It's good news. The evidence is becoming substantial that this is a milder version.

https://twitter.com/sailorrooscout/status/1475097966939721729?s=20

Knowing for sure that you had it is good information for your decision making going forward. There is going to be a lot of studies on when you will need a booster under different circumstances, and it is certainly possible that a breakthrough case will provide more durable immunity than vaccination alone.

In regards to vaccinated individuals being able to transmit COVID-19 compared to unvaccinated (naive), the evidence still suggests an unvaccinated person is more likely to spread it compared to a vaccinated person. Viral load is going to be similar for a period of time in both people, but a vaccinated person is more likely to shed virus for a shorter period of time, and the virus they shed is going to be less likely to be infectious. If the virus particles are covered in antibodies, they won't be able to infect new cells. https://www.medrxiv.org/content/10.1101/2021.07.28.21261295v1 https://www.medrxiv.org/content/10.1101/2021.08.20.21262158v1 https://www.medrxiv.org/content/10.1101/2021.08.30.21262701v1

Wow. The kicker ftw.

WTF was that? Why wouldn't you try to get a few more yards and make it easier on your kicker?

Well shit.

Data out of UK suggests it takes 2 weeks for a booster to reach full effectiveness.

The formulation is the same in the booster and original shot.

Moderna released a press release addressing this just today. https://investors.modernatx.com/news/news-details/2021/Moderna-Announces-Preliminary-Booster-Data-and-Updates-Strategy-to-Address-Omicron-Variant/default.aspx A couple of interesting tidbits in there: And related to your question: Keep in mind the multivalent candidates contained prior variants and not omicron. Our immune system really is amazing, isn't it?

Really? What immunological benefit do you think they will get from a booster this close to infection recovery?

Yes. He either makes a bowl game or he is gone.

Based on the results the last three years at GT I'd say no.

Long suffering Georgia Tech fan here. As much of a dumpster fire the last three years have been, Coach Choice was one of the few bright spots. He was by far our best recruiter and the only position group that seemed to make any progress was RB. He was instrumental in landing Jahmyr Gibbs who was our most highly rated recruit since Calvin Johnson. He, by the way, is in the transfer portal and it wouldn't surprise me to see Choice try to bring him to Texas. You all landed a good one. Our hope as GT fans is he gains experience at big time programs for the next several years and returns to GT as an OC or head coach one day. He is that well regarded among the fanbase.

Citation: https://jamanetwork.com/journals/jama/fullarticle/2787447 Summary: you get a very robust immune response after a breakthrough infection, perhaps as good as the hybrid immunity we see after a recovered individual gets vaccinated. And on top of that, there is a substantial increase in the class of antibodies (IgA) expressed on mucus membranes (like in your nose and respiratory tract) that is markedly better than what is achieved through vaccination that should do a better job at preventing infection. This is pretty basic immunology.

I wouldn't get the booster. Your infection served as the booster.

The single shot she got from Moderna should have provided her with a substantial boost and will bring her up to roughly the same level of protection as someone who had 3 mRNA shots. And I'm only talking about antibody response here.....her T cell immunity might be preferable, but we don't have solid data to know this for sure right now. Source

Your antibody level will determine how likely you are to become infected and also, to a lesser extent, how likely you are to have a severe case. Keep in mind you need a lot more antibodies to prevent infection than you do to prevent severe disease. Unfortunately we now know protection against infection is short lived after vaccination (a couple of months) whence why people are concerned about the numbers. However, protection against severe disease and death are certainly going to last significantly longer and I think this protection is being undersold. The question is how long the B cells (and don't forget T cells!) will last to protect against severe disease. They certainly will last more than a year, but we don't know if there will be appreciable numbers at 5, 10, 20 years or longer to protect against severe disease. That's why some vaccines require regular boosters (like the Tdap that is given every ten years or after exposure) to replenish the B cell and T cell populations that normally die off. It is too early to say what time periods COVID vaccines will be necessary going forward, and what the vaccination schedule will look like for optimal results. I wouldn't be surprised if we see recommendations that mix different vaccine technologies like adenovirus vector (J&J), mRNA (Pfizer, Moderna), subunit (Novavax) and perhaps other technologies that are currently being explored (DNA vaccines, for example) and hammer down scheduling when the shots should be given. We are a long way away from knowing what the optimal solution is here, and we are years, perhaps decades away from fully understanding it unfortunately. Affinity maturation doing work.