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Pods

Certifiably Surly
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Everything posted by Pods

  1. That's what I would do if I was exposed to higher risk scenarios, or patients, as well. The non-valved aren't that bad.
  2. The surgical are all too small to fully cover them and wind up being pulled really tight against the valve. The majority of the air winds up being forced through the mask, rather than diverting out the sides, which is one of the big problems with most cloth and surgical masks. I'm sure it's not N95 level protection on the exhale, but it's pretty good. It's also a lot more comfortable, so I wear it consistently. Mileage may vary for smaller faces though.
  3. I rock that with a paper surgical over it.
  4. I got called up there a number of years ago when they were scanning the Archaeopteryx feather. https://www-ssrl.slac.stanford.edu/content/sites/default/files/documents/science-highlights/pdf/archaeopteryx-201005.pdf It felt like I was in some Bond villain's underground lab the whole time. It's a huge loop of stuff that looks like this the entire way around it. Crazy ass machinery and electronics everywhere.
  5. I wear two every time. The N95 protects me, while the surgical mask filters and breaks up the valve outflow to protect others. It still vents really well and is much more comfortable to wear, while keeping the N95 underneath "clean" for the next use.
  6. JFC, cloth mask is better than no mask. N95's are better than cloth. I wear a valved N95 with a surgical mask over it and have recommended it repeatedly on here. A lot of lives would have been saved if Trump had used the Defense Production Act to produce N95 masks for everyone and distributed them. Biden should have done the same thing. That said, primarily aerosol spread doesn't mean it doesn't spread via droplets as well. That's Texags level logic. Wear the best mask you have access to.
  7. Even if Delta is no more severe, it is clearly MUCH more contagious and many more kids are going to contract and spread it. Pediatric hospitalizations are already up sharply, before you add any of this unmasked in school stupidity. If you look at the recent hospitalization trends from the CDC, it's clear as day that Delta is very different than OG, or previous variants for kids.
  8. Unfortunately, doesn't look like they calculated absolute breakthrough/re-infection rates and I'd revise my earlier post to reflect that if I could. They appear to have collected the data as visits, rather than individual patients. I don't know if they have individual patient data, but they didn't report it directly, Table S2 was as close as they got, but this is for visits, not individual patients.
  9. Oxford pre-print just came out comparing vaccine effectiveness for Pfizer and AstraZeneca compared with unvaccinated, previously infected in the UK. The data runs through August 1, so it gets both Alpha and Delta. 2-dose Pfizer provides superior protection to a recovered natural infection for either Alpha, or Delta. https://www.ndm.ox.ac.uk/files/coronavirus/covid-19-infection-survey/finalfinalcombinedve20210816.pdf
  10. Oxford pre-print just came out with that data for the UK comparing Alpha and Delta. The data runs through August 1. 2-dose Pfizer provides superior protection to a recovered natural infection for either Alpha, or Delta. https://www.ndm.ox.ac.uk/files/coronavirus/covid-19-infection-survey/finalfinalcombinedve20210816.pdf
  11. Fuck off Fozzz. Your entire schtick as a poster is willfully obtuse. I've already posted data showing variants cause re-infection in previously infected people countless times over the past two months of dealing with you and GRHorn's disingenuous bullshit. There is no herd immunity without a robust vaccination regime and boosters. There was debate about this 2 months ago, there is no debate about it now.
  12. cross posting this Not a doctor disclaimer... There are no studies using mRNA vaccines to boost J&J. There is data for Pfizer as a booster for AstraZeneca. It is safe and highly effective. Some people mixed mRNA for their initial vaccinations. Several western countries did as well. All indications are that it was safe and effective, but no studies were done. The CDC is just starting a study to look at mixing and matching different vaccines and booster shots. Insert my obligatory complaint that the CDC has been way too slow at everything. Until that data comes in, the CDC/FDA and most doctors are going to be cautious. The limited data available says it is safe and effective, but they aren't going to recommend it until they have lots of data to stand upon.
  13. Not a doctor disclaimer... There are no studies comparing mixing and matching mRNA vaccines, or using them to boost J&J. There is data for Pfizer as a booster for AstraZeneca. It is safe and highly effective. The CDC is just starting a study to look at mixing and matching different vaccines and booster shots. Until that data comes in, every US agency and most doctors are going to be cautious. They'll likely advise patients to take the same booster as the first two vaccines. They'll also likely tell you to take the other one, if it's the only one available, because the limited data available says it is safe and effective.
  14. Fucking idiots.
  15. My immune compromised relative had the same experience at CVS, no questions about underlying conditions. Had Pfizer the first two, Moderna for this one. 1.5 days of very tired and now back to normal.
  16. Now I lay me down to sleep I pray the Lord, my blood will keep Unvaccinated, clean and pure No mask upon my face, good sir.
  17. The vaccines are better at stopping Alpha and OG Covid, than Delta. Breakthrough rate with Alpha was around 1%. It happened, but was much less common than it looks to be for Delta. If Alpha were still the dominant strains, we would likely not have to have boosters yet. Delta enters cells and produces much higher viral load rapidly. It is much more contagious, so it's bumping up the timeline.
  18. This is a good post. Delta evolved sometime in October 2020 in a non-vaccinated population. It has not evolved to evade the vaccine, because it predates the vaccine. It just happens to be a really nasty fucker that causes very high viral load very quickly. That is causing infections, but the vaccine is strongly protecting against severe disease and death. Some of the nasal vaccine candidates might help this down the road by producing a stronger response in the respiratory mucosal lining. That said, if someone told us 18 months ago the vaccine would only be 40% against transmission, but WAY over 90% for preventing severe disease progression and closer to 99% on preventing death, we would all take that and be celebrating the way we would if we found out they cloned VY and he's committed in the next recruiting class.
  19. I've spent the last couple of months on this thread laying out the case that everyone was going to need a booster. There wasn't much published material to support my hypothesis, so not everyone believed me at the time, but no one reading this thread should be surprised, or not know what to believe at this point. The vaccines are still kicking the shit out of severe disease and deaths, they just don't stop as many transmissions as we'd hoped, especially Pfizer. For now, Moderna seems to be a bit better. Booster shots will greatly reduce the number of transmissions, and hopefully improve patient outcomes further. In the past few days, Israel has released preliminary data and expects the booster shot to cut breakthrough infections in half. I've discussed it on here. Today, Pfizer released their booster shot trial data to the FDA. The third dose gives “significantly higher neutralizing antibodies”. I don't know the amount, but the government does. After receiving the data today, they immediately announced they are going to authorize further boosters, so it's a safe assumption the results were very good. If anything, we should all be excited that the CDC and FDA are finally starting to pick up the pace and recognize the threat. They work great with historical data, but need to be estimating future evolutionary trends and working in probabilities to keep up in a pandemic. This is big step in that direction and I hope it continues.
  20. If history is any guide, and it's always a guide, it was GQP that fucked up the Afghanistan operation and let bin Laden escape to Pakistan, living happily ever after until Obama took his ass out. The war was lost the moment bin Laden slipped away. Catch him quickly and GTFO. By the time we finally took him down, he'd already shattered a lot of our mystique and taken a lot of the awe out of facing the US military.
  21. The Texas GQP is a hydra. Strike down Abbott and either West, or Huffhines will take control. Those guys will make DeDipshit down in Florida look competent.
  22. You're right, it does. So the effectiveness against infection is likely under that, putting it more in line with the other data.
  23. Good news on authorizing more boosters. Nice to see the FDA and CDC picking up the pace a bit and taking this more seriously, more quickly. I hope it continues.
  24. That's possible, but it is not at all the most likely outcome. Covid takes forever to kill and the virus has reproduced many times over before the patient dies if they are going to. It has reproduced so many times that whether the patient lives or dies is irrelevant. There is no selection pressure to prevent it from killing 30%, so long as it still takes a long time to kill the person. That doesn't mean it will evolve to become more deadly, but there is no selection pressure preventing it.
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