triplehorn

Correct. It's a potential risk vs potential benefit decision. Since the chloroquine exposure should be brief (5-10 days tops), that should help reduce the risk of side effects vs longer term use. Chloroquine has been around a long time and from I gather has been taken by tens of millions of people. If the incidence of dangerous side effects were particularly substantial, healthy people wouldn't be taking it for prophylaxis against parasites all these years. There's obvious contraindications related to cardiac condition and combining with other meds that could disrupt your heart rhythm. Getting the sign-off by your physician first is important. I presented mine with emerging medical publications, albeit absent controlled studies, and they understood and supported having a small amount on hand, with a hope to be able to discard it later without use. I just planned on holding it in the event I contracted coronavirus. We're neighbors with WA and Portland metro was one of the top 3-5 hot spots in the US even two weeks ago. 67% of the state's cases are within a 15-20 min drive of me in three directions. Felt like invasion of the body snatchers the last two weeks because I understood what was already present. My breathing symptoms are in a holding pattern and been obvious for 4 days now. It feels like it could get worse but it hasn't yet. I do think I'm going to be ok from whatever this is (not able to get tested for confirmation). fwiw Ive never had pneumonia, dont smoke and can't remember the last time I had anything resembling chest involvement with any bug. Chloroquine with zinc may not be doing anything, just don't know. I'd start taking some zinc alone in advance regardless.

Everyone stay home first. Just have to cut social contacts by 80%, not 100%. Unless you're having notable difficulty breathing, or have other urgent symptoms, testing actually complicates things for the general population right now.

I'd be consulting with the Germans right about now. They're doing something to minimize losses despite comparable total case numbers.

Again, Italy didn't start national at home shut down until March 9th. It can't be overstated how vital that time difference is between us and them if we shut it down today. Every damn day leads to massive containment and reduction of morbidity and deaths.

that's not going to be enough edit: Fauci didn't say 12,700 in that clip. I hope that's being misstated. edit2 : looks accurate dammit

I think that's the best path. 80% will have mild symptoms only. Stay home whether you think you have or haven't had it - it carries the same recommendation if you don't need hospitalization. Everyone cutting all social contacts by 80% is the single most effective thing we all can do starting today. If you get sick at home and the level of distress puts you in the red zone, get tested and evaluated for possible hospitalization - with either isolation or on a soon to be designated Covid ward.

Old yeah didn't click first. Don't have a link, but key on the "The Strategic National Stockpile" and LTV-1200 Ventilator. I expect there is going to be some kind of distribution method, but odds are it will be uncoordinated. Probably better to get out front if its at all possible.

@ChiTownDoc - also look here : The Strategic National Stockpile—The LTV-1200 Ventilator. Had this program since 2001 evidently

For the state of WA, getting hit hard first and mobilizing for extra ventilators is like the sole preppier hitting Costco over 2 weeks ago. Watching WA Gov. Inslee talking about this week before last, there was a moment when I sensed he was thinking ahead about the bottleneck while not saying it out loud. At least that was my spontaneous thought.

That's what's already happening in my PCP group/community who I called last week w symptoms. They're acknowledging it's been at community acquired levels here for at least a week or two (at least). Family medicine offices are asking people to come in for testing only if you need to be evaluated for possible hospitalization. Otherwise stay home assuming you have it and to not spread it (and if you don't have you prevent getting it). They also are trying to start to conserve supplies, like not having to gown and glove up repeatedly.

Never forget. Don't let accountability get shifted. Form May 2018, this bears repeating:

Italy mandated its total lockdown on March 9th. If we started a national lockdown today, comparatively it would be a massive advantage in outcome visible even 20 days from now. Every single day we wait has major effects on outcomes: So don't wait for official decrees. Make informed personal choices starting today.

15 min Covid test: Taiwan scientists develop antibodies for 15-minute Wuhan virus test in 19 days edit: this may be the one that berlinerbaer mentioned up above that SoKo is using. Either way, zero to field in 19 days. Now about that time we can't reclaim

Note that's a national aggregate.

I post this relating to the tinyurl links in the middle. Good quick reads in each one. The larger thread that Sinclair made is also interesting. Sinclair is probably best known for his work on the molecular biology of aging. From that 'therapies' one: "Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-β, convalescent plasma, and monoclonal antibodies. "

Another write-up: Of chloroquine and COVID-19 Basically it says we need to see the Chinese data to substantiate their reports. It should be noted however that SoKo and Italy both have also employed chloroquine in their management, so the power of clinical observation is motivating their treatment right now. Two days ago I started taking a prescription of chloroquine for off-label use of a presumed active Covid infection from an understanding physician. I don't have signs of progression to pneumonia so far - the biggest fear - and I feel better today than I did the last 3 days when it was mildly harder to breathe. The risks of lung involvement seem a lot worse than any side effects of of chloroquine. No idea if its related to any changes in how I feel but grateful its not worse right now

Symptoms are created by the body as a product of response to an infection. Different people's bodies can produce different symptoms to the same bug, which can be pretty specific or range greatly in some cases like we're seeing with Covid, and can include minimal or no perceivable symptoms of infection. However an actual test can prove the bug is present using a microscope, or in the case of Covid, spotting its genetic material with a test from a swab of your nose, throat, sputum, or as it turns out stool. Being immune is when the infection is over, symptoms are gone, and the immune system retains a lasting memory of that initial infection. You won't visibly find the bug or readily find its genetic material in a sample. You can test blood at any time and look for the presence or absence of immune memory in the form of antibodies which can indicate if you have been exposed to a bug or not, even if you have no recollection of ever having had symptoms.

on it. I'm taking it daily though for presumptive active sars-cov-2 infection.

There were several different news outlets based in the Philippines that reported yesterday on a medication that allegedly is showing promise in helping to overcome severe Sars-Cov-2 infection. CNNPhilippines article here. The drug is called Cycloferon. Abstract from a 2015 Russian article on it: Abstract Results of the use of cycloferon, a low molecular weight inducer of interferon production, for the treatment and prevention of influenza and acute respiratory viral infections (ARVI) in adults and children are presented It was shown to reduce symptoms of these diseases and their duration, correct disbalanced activity of the immune system, prevent complications, decrease the frequency of influenza and ARVI. The effectiveness of cycloferon did not depend on etiology of the disease. ---> "disbalanced activity of the immune system" sounds like "cytokine storm" we've been hearing about in the severe Covid cases. We know about 80% of cases of this are mild and then there's a minority, albeit very significant in numbers, that have a very complicated course that can be fatal, or if not fatal result in scarring of the lungs (fibrosis) which is a bodily response. If Cycloferon targets neutralizing those cases that would otherwise run amok, that would make sense as an intervention. If there's some validity to this, any validity at all, it would certainly be welcome news.

Russian article from 2015 re Cycloferon: The Use Of Cycloferon For The Treatment And Prevention Of Influenza And Acute Respiratory Viral Infections Abstract Results of the use of cycloferon, a low molecular weight inducer of interferon production, for the treatment and prevention of influenza and acute respiratory viral infections (ARVI) in adults and children are presented It was shown to reduce symptoms of these diseases and their duration, correct disbalanced activity of the immune system, prevent complications, decrease the frequency of influenza and ARVI. The effectiveness of cycloferon did not depend on etiology of the disease. interesting

@TheStoicPaisano use your words, buddy. What's the problem? CNNPhilippines is reporting on it as well: The Link Cylcoferon is an Russian made OTC med listed on Drugs.com

Letting this go after this - Cicloferon appears to be an OTC cold sore med containing acyclovir, used to counter herpes virus. Multiple PH online sites reporting on this alleged interview with RU Amb. to PH, but could all be fake afaik. f it. edit: I'd just add that we are getting genuine sharing and cooperation from the medical scientific communities around the world including China and SoKo. If there were any hint of progress at slowing this with a med, we would know, obviously. Edit2 : it's Cycloferon and it not acyclovir. And it's real evidently. available on drugs.com

(SIAP) But evidently the Russia Covid cure found its way to China too: Russian pharma to donate drug to treat infection wtf. slap me again.

Not sure if your response was directed at my RU/PH posts last page, but I had to reach back to page 65,66 to see anything RU /China related and nothing that involved RU possessing an advertised Covid cure. And the only PH related was a RayDog post, but only because he's pimpin' down there. What else did I miss? This quote from the Manila Bulletin: “Our medicine is as potent as our weapons,” he added and reminded Filipinos, particularly the Cebuanos not to panic because Russsia is ready to supply the country with the medicine which is highly-effective for treatment of patients infected with COVID-19." wtf? We know RU already deploys Polonium tea and Novochok. Bioweapons research just closes the loop. I have zero doubts Putin would have any scruples about using human subjects for research, i.e. prison population in Siberia. I simply cannot believe Russia has an OTC medication that neutralizes/cures Sars-Cov-2 infection. Is the Manila Bulletin even real? Somebody slap me.