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Anastasis

Certifiably Surly
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Everything posted by Anastasis

  1. What is the fascination the billionaires have with artificial protein projects?
  2. That shit sounds totally horrible. Would like to see more info and deep dive than a tweet, but that all sounds crazy.
  3. I don’t think Rfk cares one way or another. People can read your post on this page and then read mine and assess which one they find more relevant and valuable to understanding what is taking place at nih.
  4. This is what’s being referred to clumsily and imprecisely in that clip. Yet to be seen if they can land it. https://www.nih.gov/news-events/news-releases/hhs-nih-launch-next-generation-universal-vaccine-platform-pandemic-prone-viruses Thursday, May 1, 2025 HHS, NIH launch next-generation universal vaccine platform for pandemic-prone viruses Image Colorized transmission electron micrograph of influenza A/H1N1 virus particles. The U.S. Department of Health and Human Services (HHS) and the National Institutes for Health (NIH) today announced the development of the next-generation, universal vaccine platform, Generation Gold Standard, using a beta-propiolactone (BPL)-inactivated, whole-virus platform. This initiative represents a decisive shift toward transparency, effectiveness, and comprehensive preparedness, funding the NIH’s in-house development of universal influenza and coronavirus vaccines, including candidates BPL-1357 and BPL-24910. These vaccines aim to provide broad-spectrum protection against multiple strains of pandemic-prone viruses such as H5N1 avian influenza and coronaviruses including SARS-CoV-2, SARS-CoV-1, and MERS-CoV. “Our commitment is clear: every innovation in vaccine development must be grounded in gold standard science and transparency, and subjected to the highest standards of safety and efficacy testing,” said HHS Secretary Robert F. Kennedy, Jr. The program realigns BARDA’s operations with its statutory mission under the Public Health Service Act—to prepare for all influenza viral threats, not just those currently circulating. “Generation Gold Standard is a paradigm shift,” said NIH Director Dr. Jay Bhattacharya. “It extends vaccine protection beyond strain-specific limits and prepares for flu viral threats – not just today’s, but tomorrow’s as well – using traditional vaccine technology brought into the 21st century.” Generation Gold Standard, developed exclusively by NIH’s National Institute of Allergy and Infectious Diseases (NIAID): Recalibrates America’s pandemic preparedness. Unlike traditional vaccines that target specific strains, BPL-inactivated whole-virus vaccines preserve the virus’s structural integrity while eliminating infectivity. This approach induces robust B and T cell immune responses and offers long-lasting protection across diverse viral families. Moreover, the intranasal formulation of BPL-1357 is currently in Phase Ib and II/III trials and is designed to block virus transmission—an innovation absent from current flu and COVID-19 vaccines. Embodies efficient, transparent, and government-led research. The BPL platform is fully government-owned and NIH-developed. This approach ensures radical transparency, public accountability, and freedom from commercial conflicts of interest. Marks the future of vaccine development. In addition to influenza and coronavirus, the BPL platform is adaptable for future use against respiratory syncytial virus (RSV), metapneumovirus, and parainfluenza. It also offers the unprecedented capability to protect against avian influenza without inducing antigenic drift—a major step forward in proactive pandemic prevention. Clinical trials for universal influenza vaccines are scheduled to begin in 2026, with Food and Drug Administration (FDA) approval targeted for 2029. The intranasal BPL-1357 flu vaccine, currently in advanced trials, is also on track for FDA review by 2029. About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.
  5. Batshit crazy 10-20% of the time was the other part of that. BTW. Flu shots started shipping last month. I know that some posters were really worried about that this year. Already in some pharmacies. Don't forget to get in early and get your shot before the season gets wound up.
  6. Imagine not even keeping count.
  7. You can disagree with anything you like. Doesn't really change the real world evidence.
  8. How many shots did you take and how many times did you have COVID? mRNA tech needs to be kept in the stable, the rapid response capability is important. But it has not proven out to be a particularly durable solution. We need sterilizing vaccines, IgA eliciting nasally administered vaccines, and traditional subunit protein vaccines to round out. Everyone should now be basically transitioning to novavax for covid until a nasally administered sterilizing vaccine comes to market. Shifting the research dollars is appropriate, but mRNA needs to be kept in the back pocket.
  9. Lawfare is an interesting cite in this context. Poor track record wrt their prior pieces falling flat and Brookings Institute all up in this shit.
  10. Would be more useful to report absolute dollar amounts. Here is the permian basin balance sheet: https://www.basinpbs.org/bento-api/filer-file-download/393324/ Not sure what their viewer rankings are, but they need to step up their membership numbers to close the gap that will result.
  11. faces of fetal alcohol syndrome.
  12. Not sure why the neg. Brisket was coddling gop balls when it was cool for him.
  13. My decades as a Republican are far less than yours. Like orders of magnitude.
  14. I understand that you are out of your depth.
  15. Is this the part where you flex your broke brain? What a ride. Enjoy.
  16. You should just hold out for state department talking points to tell you what to think.
  17. It’s also why you are so loud all caps blustering. You think no one sees it brisket. Buts it’s all pretty obvious.
  18. Your politics are responsible for where we are today. You’re too cracked up to recognize it though.
  19. It’s good polit It’s political fodder for our broken system. I know that you see this as a one side issue. It’s not. They all play the game. We have broken politics. It absolutely is a swinging pendulum. But maybe ALL CAPS WILL FIX IT.
  20. Must have been where you and Jacinda Ardern broke ways. Every nation must be able to control their borders. Our politics are too broken to land reasonable solutions so the pendulum swings. One way and then the other.
  21. I am sure you are tracking.
  22. Agree. It’s really amazing. I see the hoops that people have to jump through to work here. These are people with PhDs and MSs trained in US schools. They get in line and play the game and pay tens of thousands of dollars to lawyers and others to navigate. It’s all nonsense. But have you looked into the process in New Zealand?
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