Yes. Dems should quickly state how each candidate is inadequate for the task, if not openly harmful and then add documentation for the rest. Call out Gaetz for his involvement of sex with underage girls and that Gabbard has a too-close relationship with foreign adversaries. Then document the hell out of everything in the senate filings for future historians. Does that change anything today? No but the Dems can't stop the process and attempts will waste political capital.
Democrats used to be able to hold senate seats in GOP leaning, if not fully red, states but that has/is quickly ending. It makes the senate tough for them because of all of the small red states. Its why barely losing 2 seats in PA and OH 2 weeks ago so painful for them. They have to find a way to win. They also need to allow, if not force, senators like Ossoff or Warnock do more to appeal to their moderate bases. the good news is that they should be able to do so given the Dem's lack of power.