Although there is probably significant overlap, we need to differentiate between what the Estate has and what the DOJ has.
The Estate is presumably a collection of Epstein's memorabilia, not evidence collected as part of a criminal investigation. As such, it may be freely released, subpoenae'd what-have-you.
Knowing what a weird fuck Epstein was (see above), his Estate may contain evidence of a crime, or maybe not.
The DOJ stuff is evidence collected in a criminal investigation. It potentially could be withheld subject to an ongoing criminal investigation, whether real or concocted.
Despite what happened with Epstein's first prosecution, I find it very difficult to believe that DOJ is in possession of "smoking gun" evidence of a crime other than by Epstein and Maxwell, who were prosecuted. That includes CSAM implicating Trump, Clinton, or anyone else.
Most of it is association and innuendo stuff, I'm relatively certain. Some of it, like Trump's birthday card, weirder and more sinister than others.