It's up to him and the sacrifice of family time must be gutwrenching but I think after taking time, he will see that America needs him and his message. His resume doesn't matter much, look at Lincoln, who btw, was a longshot when he decided to pursue the republican nomination.
https://www.cnn.com/2018/11/08/politics/beto-orourke-2020-democratic-presidential-race/index.html
Another source described having "very initial discussions" with O'Rourke in recent weeks about the prospect of a 2020 bid and what it would take to scale a Senate campaign that operated largely on the candidate's own gut, without pollsters or a massive team of consultants, up to the national level. But the source said it's too early for O'Rourke to have made any decisions.
Publicly, O'Rourke has flatly ruled out the possibility of a presidential run.
"The answer is no," O'Rourke said at a CNN town hall in October when asked about the prospect of a presidential campaign.
"Our children are 11, they're 10, and they're 7 years old. We've told them we're going to take these almost two years out of our life to run this race, and then we're devoted and committed to being a family again," he said.
Pressed again, he said, "It's a definitive no."