Are either of you using revamped passing by chance? It's the best of the bunch in my opinion and not that hard to pick up with just a bit of practice. Here is a good article on how each passing style works:
https://www.operationsports.com/madden-25-and-college-football-25-passing-settings-and-revamped-vs-placement-and-accuracy/
Hard to diagnose exactly what's going on without more of the details. I don't want to sound like a total dick, but none of the patches have radically changed CPU coverage or interception tendencies. Based on what's been shared my guess is that there is an issue recognizing defenses and having an idea of who the best 1st and 2nd options are on any given throw. Here is another article that helps identify what coverage the Defense is in based on how they line up at the snap.
https://www.operationsports.com/identifying-coverages-pre-snap-in-madden-25-and-college-football-25/
Bear in mind that the CPU D will sometimes disguise coverages (i.e., show Cover 3 but actually be in man, etc.).
Finally, the game does have momentum such that completing shorter/higher percentage throws early on will get your QB into rhythm and result in more accurate longer throws. I open most games running RPO's, drag routes, and jet sweeps to start building momentum.