You're losing those three top 10-15 all time players, plus likely one of the historically best team USA players in Jrue Holiday. He left the team before the Olympics started, but you can also probably go ahead and cross Kawhi off too.
You can still get 10-12 all-NBA types on the team though. A lot of it is deciding which of the dozen or so qualified guards do you pick? Do we go ahead and assume health for Embiid and AD? Is Zion healthy? Is someone like Brandon Miller too good a fit at FIBA ball to keep off the team? Who replaces Jrue as the primary on-ball defender?
I'll take a stab
'C: AD, Bam, Chet (I'll go ahead and guess that Embiid is injured and AD isn't)
W: Tatum, Paolo, Flagg, Brown (I decided between a bunch of wings here, including Brown, Barnes, Bridges, Miller, but went with Brown)
G: Ant, Haliburton, Booker, White (again, you can justifiably pick a dozen different guys here, but it's probably easiest to pick players with prior Olympics success).... I'll take a heat check and take a fifth guard with Jalen Suggs, who's now one of the best perimeter defenders in the league and is turning into a good connecter, he just needs to be able to make open threes
I think by this time Ant is probably the best American player, with Tatum not far behind. So the team would be more ball stoppy and iso heavy because that's how those two play, which can be remedied a bit by starting Haliburton and telling everyone to just go (plus Haliburton adds spacing). Obviously Haliburton is a problem on defense, but so is Steph; as long as he works hard defensively, you can probably make up for it with four other good defenders around him. The other 5th starter can be matchup dependent, or maybe Paolo or Flagg has ascended at that point, or maybe it's just Booker