I'll try to give the short version from the weight loss thread. Back in 2019, after having surgery to repair a torn biceps tendon, I ballooned up to 249 lbs. Once my arm healed, I got back to working out and trying to eat more healthily, but couldn't get it kick-started. I got a prescription from my doc for Ozempic (covered by insurance) and within no time, dropped 20 lbs. From there, I stagnated for the next year. You just get used to it. After a year, we upped the dosage from 0.5 ml to 1.0 ml. Over the next three months, I lost a couple of pounds, but no major changes other than even more heartburn/GERD. Then, seemingly out of nowhere, I developed intractable hiccups. I'm talking, hiccups for three hours (bad hiccups), which would abate for an hour and start again. I was prescribed Thorazine, which did nothing to abate the hiccups and made me feel awful. I stopped that after a day or so. My doc said to discontinue Ozempic, but because it stays with you for a week or so, the hiccups continued. After about 5 days of it, I stumbled onto a Reddit where the OP said he had this problem and resolved it (after an ER visit) by taking a probiotic (Lactobacillus). Desperate, I picked some up, took two, and another two before I went to sleep, and it worked. I had maybe one more bout of hiccups, which abated quickly. I've been taking about 4 Billion cultures of Lactobacillus daily since then.
I worried about coming off Ozempic and putting the weight back on as most people do. I got very serious about my diet (during the week) and, over the next four months, I dropped another 30 lbs and have leveled out at just above/below the 200 lbs mark. Honestly, I'd like to lose a little more, but I'm not taking Ozempic ever again. Intractable hiccups was quite convincing on that score.
As with any medication, YMMV
Edit to add that my non-medical opinion is that because Ozempic causes the amount of time food spends in your stomach to increase, over time, your gut flora/fauna gets pretty wrecked and a daily probiotic would be a good idea.