I've said this before several times on here and I'll say it again, regional breweries are a thing of the past (nationally, but especially in TX). Breweries are as hyperlocal as they've ever been, and that's a GREAT thing. Brewers are treating small breweries like local bars now and laying off the pipe dream of becoming national (or regional) brands.
You want a successful brewery? Get a partner or two to help run operations. Make a cool taproom. It doesn't have to be the nicest, just warm and inviting. Self distribute, but only distribute like 5% of your beer to high volume accounts for advertising purposes. Sell the other 95% out of your taproom. Get a brewpub license and sell crowlers (or growlers, but just do crowlers i mean, come on) to-go. Keep your footprint small and get into an underserved neighborhood or community. Play good music, make it kid or dog friendly or both. Have an outdoor space.
Basically, no need to re-invent anything. Just copy/paste brands like ABGB, Southern Heights, or ABW.
That'll be $99.95
BTW, Big Bend didn't go under because of underperformance (although i thought they sucked after Steve Anderson died). Big Bend mostly went under because of this.