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  1. The Taliban is serious though in its conservatism. The GOP are just pretenders and cucks to capital like everyone else in charge of anything meaningful in the West.
  2. Just want to @ mention our friend and patriot @GRHorn here so that when this treasonous cuck incites more violence against the US government he won’t be able to say “never heard of him.”
  3. https://www.mercurynews.com/2021/08/27/new-ucsf-study-vaccine-resistant-viruses-are-driving-breakthrough-covid-infections/ New UCSF study: Vaccine-resistant viruses are driving ‘breakthrough’ COVID infections ‘As long as the virus continues to circulate, it will continue to mutate’ SAN FRANCISCO, CA. – DEC. 30: Dr. Charles Chiu of UCSF is sequencing hundreds of Northern California viruses from recent UK travelers to help understand the latest mutations. He was photographed Wednesday, Dec. 30, 2020, in San Francisco, Calif. (Karl Mondon/Bay Area News Group) By Lisa M. Krieger | lkrieger@bayareanewsgroup.com | Bay Area News Group PUBLISHED: August 27, 2021 at 9:30 a.m. | UPDATED: August 27, 2021 at 3:11 p.m. Waning immunity and ferocious contagion are known to be fueling the troubling surge in “breakthrough” COVID-19 cases among vaccinated people. But a new UC San Francisco analysis of 1,373 Bay Area cases reveals a third, and more ominous, problem: The coronavirus is learning to outsmart our immune system. Variants with antibody-resistant mutations are playing an ever-larger role in our highly vaccinated region’s pandemic, according to research by prominent virologist Dr. Charles Chiu. His team found that 78% of infections in fully vaccinated people among the study were caused by variants with these mutations, compared to 48% of the cases among unvaccinated people, who remained an easier target for earlier generations of the virus. Overall, the proportion of cases linked to these variants more than doubled between February and June. The findings add to a growing list of studies that are unraveling why the vaccinated are still so susceptible to infection — and provide a deeper understanding of what we may encounter in the future. Vaccinated people are still much more protected from serious illness, hospitalization and death than unvaccinated people, the study confirmed. “But I worry that as long as the virus is circulating, it will continue to mutate and evolve, which will, in turn, allow it to continue spreading,” he said. The study suggests that new iterations of the virus will likely become even more resistant, over time, “until, eventually, you’re going to see the vaccine not work, or its efficacy will be reduced significantly,” he said. Our vaccines won’t suddenly become useless, he added. So far, it appears to be a gradual process. The resistant variants will slowly dominate over time, he predicted. The rollout of booster vaccines, planned to begin the week of Sept. 20, will help bolster our defense against these breakthroughs, Chiu said. But as the virus continues to evolve, he said, vaccines may need to be reformulated to keep us safe. The team’s second major finding was more reassuring: People who never develop symptoms during a “breakthrough” infection carry very low levels of virus – a finding that should ease concerns that vaccinated people are unknowingly fueling the pandemic. However, vaccinated people who do have symptoms had the same levels of virus as infected unvaccinated people – so can spread the virus. This confirms a finding first revealed weeks ago by a CDC study in Provincetown, Massachusetts. “You’re essentially as infectious as someone who was unvaccinated,” he said. The UCSF team performed genome sequencing of viral samples from Bay Area residents who sought treatment for COVID-19 at UCSF hospitals and clinics between Feb. 1 and June 30, as well as people whose infections were detected at community test sites. Of these, 125, or 9.1%, were vaccine “breakthrough” cases. The study, published as a preprint on Wednesday, has not yet been peer-reviewed or corroborated by other investigators. A great concern is the study’s observation that vaccinated people infected with these “escape mutants” can likely transmit them to others, including the vaccinated, said infectious disease expert Dr. Gary Schoolnik, a clinician and professor of medicine at Stanford Health Care, who was not involved in the study. “The implication of their finding is that vaccine-resistant mutants of the COVID virus could disseminate more widely in the population,” he said. “If that were to occur, it might necessitate the development and use of COVID booster vaccines that specifically target such mutants.” Overall,three factors are driving breakthroughs, according to Chiu, director of the UCSF-Abbott Viral Diagnostics and Discovery Center and associate director of the UCSF Clinical Microbiology Laboratory. One is exposure to the large number of viral particles shed by those infected with the delta variant. People infected with delta may shed approximately four times more virus than those infected with the original virus. A few of these viruses can slip by our antibody defense, causing infection. Another is waning immunity, according to recent Moderna and Pfizer vaccine data. Six to nine months after vaccination, our bodies produce fewer effective antibodies. The third reason is this newer and worrisome trend: infection by a variant carrying resilient mutations. The new study found that the proportion of cases caused by these variants increased over five months from 40% to 89%. The team did not study the effect of the mutations on the effectiveness of the other arm of the immune system, involving T cells that kill the virus. Vaccination is not to be blamed for the increase in variants with these mutations, Chiu said. Because we naturally produce antibodies in response to exposure and infection, the virus is constantly changing to survive. “The virus is going to evolve to become antibody resistant, whether or not you deploy a vaccine,” he said. “But because we have a vaccine, there’s a way to prevent the virus from spreading and evolving further.” One of these mutations, L452R, is built into the genetic code of the dangerous delta variant, which now dominates. But this and other mutations, including E484K and F490S, can be carried by other resistant variants, such as beta, gamma, epsilon and lambda. Our antibodies are less effective in fighting off variants carrying these mutations. These mutations don’t render our antibodies useless against the virus. Resistance is almost always partial; it’s not an “all or none” characteristic. “This decrease in vaccine efficacy due to infection by a resistant variant can be minor, or significant,” he said. The mutations make it tougher for antibodies to bind to the virus, so the virus is able to slip through and infect a cell. More of them are needed to neutralize the virus. A booster dramatically increases our levels of antibodies. A new and reformulated booster, targeted for a particular variant such as delta, could push them still higher. Ultimately, we will control this pandemic by vaccinating as many people as possible, Chiu said. "Otherwise, if the virus continues to circulate and mutate,” he said, “this may become a never-ending round of whack-a-mole.”
  4. Did somebody Tweet back and ask if they had ever heard of beta testing?
  5. Fucking hell their fans are just hardwired to be betas. “Hey Daddy! Is other daddy winning a recruit really a big deal? Please tell me how to feel even though we are not involved!”
  6. What a fucking moron. Does he not realize by being left out of the cuck coalition, the big 12 is licking glass right along with window coug? The big 12 will be passed over continually. An expanded playoff is there best option in getting into the playoffs more than once every quarter century....
  7. Yeah JSD, if your mom dies, she dies. Stop worrying about it you beta bitch
  8. Yeah it means you’re a beta cuck soy boy simp.
  9. yeah potato does good stuff. you know the duder or just mean you following on YT? big CIV fan here for some time. Have been at HK for some months on betas and now in the real. Fun game. Very layered and of course very new and unbalanced. I understand its a bit "if you built it they will come" in terms of the various mechanics for now. Saying that it does feel a bit hollow to me so far. Very easy to survive and thrive and the scale via the various cultural buffs. the early game is however pretty challenging and many of the AI guys can snowball then too. fun game. lots of great stuff
  10. Yeah no, c'mon man she deserved to be ridiculed, but hitting her for her asinine yelling no. I put this squarely on her husband who didn't tell her to STFU, and pull her away. He is or should be labeled a cuck. I'd be telling my wife to STFU, and sit down or go take a walk, and cool off because your shit is getting ready to get me in a fight, and I don't want any part of that over something happening at a football game.
  11. I've seen this play out exactly on Pornhub, the three went home together and bro fucked the wife in front of the cuck husband.
  12. I get it. You’re a beta cuck pussy that spends his days in the cloak room jerking off Denison but in the real world actions have consequences but the fact that you went so triggered by it tells me your hair is purple and your Facebook badge celebrates your vaccine status.
  13. Stupid people who like to call other people betas then run away with hurt feelings if you don't agree. It's an army of spineless punks sprinkled with some really dangerous psychopaths and cynics just raking in the graft. Sadly, it's a juggernaut.
  14. Those guys have a low beta. I have a high beta. I’m a 10.8 index and my average score is around an 86 at my home course. But on any given day I can shoot a 95 or an 82. My low round ever is a 77.
  15. imagine being such a beta-cuck that you incessantly rail against a politician in your safe space, and the second the thread you've hijacked with politics is moved to the politics board (where you'll be asked to defend your assertions), you scurry off like a cockroach. what's up with that @BabaYaga? why are you such a snowflake?
  16. I ain’t calling in shit. This parent wears this kinda shit as a badge of honor. An arrest probably furthers the martyr status. I feel bad for the teacher. Real fucking fun coming to work each morning having to look over your shoulder from the faculty lot to your classroom. The spouse In question is a real beta cuck, the kind ‘real Texas men’ make fun of even though they all have a wild amount in common. Might be cathartic to shove a mask in his mouth while beating the shit out of him to square up karma.
  17. . . . only talking sense. Very Beta white dude - ass up - under her skirt. That Chinese Tiger thingybop is thirsty for a bottom. Don't look into his three eyes.
  18. Chad Advice: Alphas don't lean towards an other man - only Betas do that with another man.
  19. I hate Ron Paul. HATE. I worked in Congress when he was a member of our delegation. De. Spies. but to paraphrase him: They don’t hate us because we love freedom, capitalism, and titties. They hate us because we are over there. For all you pro occupation cucks: you are arguing we should occupy a country indefinitely to protect our nation. This isnt fucking German, they aren’t an ally. The only people who like us in Afghanistan are the elite who rely on us to be muscle for their klepto state. we’ve spent Close to 3 trillion in that country. You could replace America’s highways from coast to coast, harden all our ports and airports, and still have cash for Medicare or school improvement with that kind of coin. We lost. You can either wallow in your shit or get on with the future. There is no victory, just an endless occupation, while the Taliban shadow controls the country side and we live in denial of the human and treasure cost of our folly and debacle.
  20. Not a doctor disclaimer added, but I would expect you likely have pretty good protection. The J&J data out of South Africa was decent against Alpha and Beta. The booster data I've seen for the mRNA vaccines shows a substantial immune response against Delta. I haven't seen any data on boosters with J&J, but will keep my eyes peeled and post if I do. Two things to think about. 1) There may be a substantial increased immune response if you delay the second shot. There's evidence emerging that this is the case for mRNA. It may, or may not apply here. 2) You may not need one for 6-8 months and getting the second one now may limit when you can take the next booster. I'm not sure what I'd do personally, if I was in your shoes, but I would likely wait until a little more data comes in depending on my viral exposure. If you are healthy with no co-morbidities and reasonably confident you can keep from getting infected for a few weeks, I'd wait and see if some more consensus emerges.
  21. Listen Incels and Cucks, You cannot apply today's cancel culture and anti-rape messaging to the past. I mean, was rape even a crime back then? /Bob Stoops and Joe Mixon's attorney.
  22. they won't learn any lesson. california coastal exceptionalism. the cigars of those schools watched larry scott set a course for the sun. tree and cal will quit d1 football before they will consider weaponizing. the pac is doomed. the old pac8 will go down with the ship, USC will go indy, and the entire Cal and Cal State systems will drop to d2 or quit altogether. washington & oregon are fucked. wastate and orgstate are turbofucked. the cards are with utah, colorado and arizona state, with arizona along for the ride. that's who the ir8 need to be pushing hard with, all-in, and doing it creatively, with apple or amazon as the backchannel. the streamers need a beta test for the new world and a mountain-something is perfect.
  23. Cucks aren’t known for being very assertive
  24. Ecstatic about the move. Texas belongs in a conference that is passionate about football. This should greatly benefit benefit recruiting, along with NIL. Also, it was an added bonus to see aggy cucks lose their minds. As far as locations, I don’t really care for CS, Louisiana, or Mississippi, but I’m looking forward to games in places like Florida, Georgia, Tennessee, Kentucky, and SC.
  25. Viagra + Vaccine = Alpha with big pp. Viagra + No Vaccine = Welcome to pegging, cucks.
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