CR: COVID-19 --Political Talk

[PsychMike 1552]

I always thought Dick Trickle should've become a urologist instead of race car driver.

[HornOnTheBayou 8945]

I have really appreciated the work of Dr. Freely in raising awareness of uromysitisis and promoting free-range urination in parking garages.

[Dnaguy 12057]

51 minutes ago, Anastasis said:

No fake name will ever top Dick Chopp. 

 His good buddy is Dr. Imus Maphorskein

[Bama Chick 28596]

2020 CAN SUCK ALL THE DICKS

[GRHorn 105]

On 10/13/2020 at 2:14 PM, Bozo_Casanova said:

Yawn

[Anastasis 23484]

More on immunity and re-infection...

https://blogs.sciencemag.org/pipeline/archives/2020/10/14/immunity-and-re-infection

 

[F]rom everything we can see, re-infection is a very rare event. The confirmed examples worldwide could possibly be counted on your fingers (depending on whose count you believe) out of at least 38 million total cases. Looking at the Netherlands case, this was an 89-year-old patient with Waldenström’s macroglobulinemia, a type of leukemia that affects two different varieties of B-cells. She was being treated with chemotherapy to impair. B-cell production, and was thus immune compromised, and the second infection occurred two days after her latest round of treatment. Below is an analysis of the sequences of the first virus and the second – if you’d like more information about what a figure like this means and how to read it, see posts here and here.

...

So the situation, for now, seems to be that yes, re-infection is possible. But it’s also quite rare. There are surely cases that we’ve missed, but it’s clearly not something that is happening much. We’re dealing with the fact that the human immune response is hugely variable from person to person – that’s one of its key features. Different people are going to raise different levels of different populations of different antibodies to a coronavirus infection, and that’s a big reason why the clinical course of disease is so variable. Even in these documented reinfection cases, we don’t know the details about what their first immune responses were like (there was no reason to profile these people in such detail the first time!)

Moving beyond that, I would suspect that vaccination, which raises neutralizing antibodies to the Spike protein, will provide a population that is even less susceptible to re-infection than we have in the wild-type-recovered population now, given that three of the five cases we have details of did not have significant changes in the Spike region at all. Now, we don’t know how long vaccine protection will last, or how variable it will be in a broad population – we’re out there getting those data now – but from what we’re seeing, I think the prospects are good. No panic necessary for now.

[Anastasis 23484]

ID docs are a little off..

 

 

[triplehorn 2664]

with those jams, his guitar case should be filled with enough donations to cover that cocktail.  ok maybe just the steroid lol.

[4th&Five 41586]

[Biff Tannen 45728]

6 hours ago, Bozo_Casanova said:

White House cites herd immunity letter signed by Dr. Johnny Bananas

The White House has reportedly embraced a declaration by a group of scientists arguing for a “herd immunity” strategy to deal with America’s coronavirus pandemic—days after the validity of the declaration came under question due to a number of apparently fake names among its expert signatories, including “Dr. Johnny Bananas.” According to The New York Times, on a call convened Monday by the White House, two anonymous administration officials cited the petition, titled The Great Barrington Declaration, which argues that COVID-19 should be allowed to spread through the population. The declaration’s website claims the petition has been signed by more than 15,000 scientists, but, last week, Sky News found dozens of fake names on the list of medical signatories, including Dr. I.P. Freely, Dr. Person Fakename, and Dr. Johnny Bananas.

JFC.  This timeline BLOWS.

Edit: I really hope Johnny Bluejeans and Senor Underpants were on there too.

Edited October 15, 2020 by Biff Tannen

[Mdhorn 5987]

5 hours ago, Brisketexan said:

......each one of whom would instantly become the most qualified person the admin has actually listened to.

No dr. mike hunt?

[heso 2816]

3 hours ago, Bama Chick said:

2020 CAN SUCK ALL THE DICKS
 

The devil coming to collect on that deal. 

[alphahorn 1637]

It's not just in the USA, real doctors all around the world are sick and tired of this bullshit

 

[washparkhorn 9939]

19 minutes ago, alphahorn said:

Please watch if you want to know what real doctors think and witness

 

Hoisted from the Comments - 

Quote

CSAcitizen Feather1 month ago: The socialist 6 foot distancing is NOT for the virus or health - it s for the A.I. identity high tech system to ID you

Looks like Qanon shit to me. 

[gmr548 16612]

I just have to laugh.
 

'Murica 2020 bby

[washparkhorn 9939]

20 minutes ago, alphahorn said:

It's not just in the USA, real doctors all around the world are sick and tired of this bullshit

 

No wonder Europe is getting hit hard by a second wave of Covid. Lack of common sense appears to be contagious.

Hoisted from the comments:

Quote

rishandproud grainne1 day ago: Bless everyone of you for speaking out against these Satanists.

 

[FondrenRoad 4378]

5 minutes ago, washparkhorn said:

Hoisted from the Comments - 

Looks like Qanon shit to me. 

One thing about this that I've found off since the start is that libertarianism used to respect the personal space of others. Why are they getting within 6 feet of people that don't want them that close in the first place?  Don't we all have our own libertarian personal space bubble around us?  Cross it without permission and get met with a justified libertarian use of force.  It should have been simple.  I actually think we've gone a little too far in allowing nearly everything to be fair game before a physical altercation. If someone is verbally attacking you inches from your face, you should have the right to throw the first punch.

Because these Karens and Kens will get right up in chest to chest fighting distance while screaming in someone's face, and think they have a right to do so without getting hit.  And all this would be over if a few of them got knocked out. 

[Hmbre97 6331]

44 minutes ago, alphahorn said:

Please watch if you want to know what real doctors think and witness

 

LOL, if anyone gets a chance, strap on your tinfoil hat and go peruse the channel that this video came from. I tried to pull a few snippets for the lulz but there was just so many..... and as I was typing that, one of the speakers just opined on how we are eventually going to have the rainbow flag on our govt issued ID's. Jesus titty Christ. 

https://www.youtube.com/channel/UCGbn8Ek1nzimFkTXZyTWfLA

[FondrenRoad 4378]

1 minute ago, Hmbre97 said:

LOL, if anyone gets a chance, strap on your tinfoil hat and go peruse the channel that this video came from. I tried to pull a few snippets for the lulz but there was just so many..... and as I was typing that, one of the speakers just opined on how we are eventually going to have the rainbow flag on our govt issued ID's. Jesus titty Christ. 

https://www.youtube.com/channel/UCGbn8Ek1nzimFkTXZyTWfLA

We already do. In Hawaii. 

[wildcat09 29379]

50 minutes ago, alphahorn said:

Please watch if you want to know what real doctors think and witness

 

Negbomb this freak.

14 minutes ago, FondrenRoad said:

One thing about this that I've found off since the start is that libertarianism used to respect the personal space of others. Why are they getting within 6 feet of people that don't want them that close in the first place?  Don't we all have our own libertarian personal space bubble around us?  Cross it without permission and get met with a justified libertarian use of force.  It should have been simple.  I actually think we've gone a little too far in allowing nearly everything to be fair game before a physical altercation. If someone is verbally attacking you inches from your face, you should have the right to throw the first punch.

Because these Karens and Kens will get right up in chest to chest fighting distance while screaming in someone's face, and think they have a right to do so without getting hit.  And all this would be over if a few of them got knocked out. 

I wish a motherfucker would try that shit with me. I’ll gladly defend my use of reasonable force in response as justified self defense. Of course those cowards typically limit that shit to people who aren’t physically capable of standing up to them.

[Hmbre97 6331]

https://en.wikipedia.org/wiki/Doctors_for_Disaster_Preparedness

Quote

Doctors for Disaster Preparedness (DDP) is a 501(c)(3) non-profit organization located in Tucson, Arizona.^[1] The group is closely affiliated with the American Association of Physicians and Surgeons, a politically conservative nonprofit association advocating numerous discredited hypotheses including AIDS denialism.^[2] It is run by Arizona physician Jane Orient.^[3]

According to Bloomberg News, the group was "founded to promote civil defense during the Cold War", and has been "transformed over the years into a forum" on "fringe-science topics" such as global warming denial.^[3] DDP was described by The Guardian as a "fringe political group" and as a "truly bizarre lobby group".^[2] It promotes the denialist view that man-made global warming is not real or not an important concern.^[2]

 

Maybe alphahorn got confused and thought he was posting those videos to Facebook since apparently that's where all the crazy olds post thier conspiracy shit now.

[Hmbre97 6331]

What I originally came into this thread for was after seeing the outbreaks occuring on some CFB teams now, I wonder if the non-mask wearing freedom patriots will start to purposefully avoid going to the doctor when sick to avoid confirming they are covid positive. As whipped up as some of that bunch is, I wonder if any of them would literally risk dying to avoid admitting they were wrong? Sorta in the same vein that Herman Cain's twitter account still posts covid hoax shit despite the account owner dying from covid.

[Beau Vine 54416]

48 minutes ago, FondrenRoad said:

We already do. In Hawaii. 

BZZT.  

[Beau Vine 54416]

32 minutes ago, Hmbre97 said:

What I originally came into this thread for was after seeing the outbreaks occuring on some CFB teams now, I wonder if the non-mask wearing freedom patriots will start to purposefully avoid going to the doctor when sick to avoid confirming they are covid positive. As whipped up as some of that bunch is, I wonder if any of them would literally risk dying to avoid admitting they were wrong?

You mean like Trump did?

[FondrenRoad 4378]

50 minutes ago, wildcat09 said:

Negbomb this freak.

I wish a motherfucker would try that shit with me. I’ll gladly defend my use of reasonable force in response as justified self defense. Of course those cowards typically limit that shit to people who aren’t physically capable of standing up to them.

Agree. They dont target people they think will fight.  

The closest I've come is at an NJ gas station. At peak covid around here.  There are attendants because you arent allowed to pump your own gas (crazy but true).  The attendant, an older eastern European guy, has a mask, we have masks in the car to protect him, he takes the card, its paid for, all seems fine.   Then he hands it back through my wife's window, pulls his mask down and says "breathe the fresh air."  She rolls the window up on his hand. I get out of the car and start to go around the car, and the guy runs away into the station. My wife was screaming at me to just get back in the car, and I eventually did,, but I still wish I followed his ass inside. And really, that was just a mild Ken. I'd be in a melee with most of the Karens and Kens I see posted online. 

Edited October 15, 2020 by FondrenRoad

[FondrenRoad 4378]

8 minutes ago, Beau Vine said:

BZZT.  

What does the Hawaiian flag have to do with the Hawaiian ID card

Edit: mclovin rainbow ID Image link wouldn't work. 

Edited October 15, 2020 by FondrenRoad

[Hmbre97 6331]

What does the Hawaiian flag have to do with the Hawaiian ID card.
https://images.app.goo.gl/YNpES7nrtAE3rTFz9

They said rainbow flag, not an actual rainbow.

[FondrenRoad 4378]

2 minutes ago, Hmbre97 said:

4 minutes ago, FondrenRoad said:

What does the Hawaiian flag have to do with the Hawaiian ID card.
https://images.app.goo.gl/YNpES7nrtAE3rTFz9

They said rainbow flag, not an actual rainbow.

Yes but they said rainbow flag on an ID. So we are halfway there. The Hawaiian ID has a rainbow on it.  It's not even possible to put a flag on an ID. You would just have a rainbow rectangle missing one of the colors. 

[troph 24905]

Wait I missed the memo that we are using covid to recruit you guys? Damn. That’s brilliant. I don’t know about sucking dicks but hey it’s 2020 we’ll all have that experience before the years out. Might as well lean in and join the club. #gayagenda

[FondrenRoad 4378]

15 minutes ago, troph said:

Wait I missed the memo that we are using covid to recruit you guys? Damn. That’s brilliant. I don’t know about sucking dicks but hey it’s 2020 we’ll all have that experience before the years out. Might as well lean in and join the club. #gayagenda

 You should really feel bad for Pence and how the gay agenda is already making him suck all those dicks against his will.  If its banned, maybe he will stop hanging out in that truck stop bathroom. 

[HenryJames 66169]

 

[4th&Five 41586]

 

[triplehorn 2664]

5 hours ago, HenryJames said:

 

The collapse of flu season due to covid mitigation (ie population masking up)  was already observed in Hong Kong last winter.  FT from March 2020 - paywall but you get the idea:

Hong Kong’s coronavirus response leads to sharp drop in flu cases;Winter influenza season ends more than a month earlier than usual

 

[MNLonghornFUKM 8817]

 

Haha this thread should be blowing up.

[Bama Chick 28596]

Good thread on how a Canadian gym did everything right and yet one single asymptomatic case caused a really really big outbreak.

 

It also illustrates how much better the Canadian contact and trace program is compared to America’s utter failure on that front.

 

If this happened here, probably 50% of those gym members would have refused to participate citing the bullshit “Muh Rights and Freedoms!” nonsense.

 

 

[PsychMike 1552]

1 hour ago, Bama Chick said:

Good thread on how a Canadian gym did everything right and yet one single asymptomatic case caused a really really big outbreak.

 

It also illustrates how much better the Canadian contact and trace program is compared to America’s utter failure on that front.

 

If this happened here, probably 50% of those gym members would have refused to participate citing the bullshit “Muh Rights and Freedoms!” nonsense.

 

 

 

There has been a distinction about the type of activity and its association with risk. For example, singing is riskier than speaking in normal volume. It's about the force of exhaling the aerosolized viral droplets. It's not hard to see how a spin class, with and even without a shouting instructor, would be on the riskier side of things. Hence the 6 ft rule should not have been considered adequate. I'm afraid sometimes simplified messaging can lead to a false sense of security. I can't think of how many times the dotard administration has said, "but they're outside!" when someone asked them about social distancing and masks.

[HenryJames 66169]

 

[triplehorn 2664]

 

Re allocation of 2020 funding for the National Institute of Allergy and Infectious Diseases (NIAID) which Dr. Fauci has headed for decades, this is interesting:

 

A whopping 81% of funds for Covid is going to vaccine research.

A mere 4% is allocated for therapeutics research which relates to studies like re-purposing drugs to treat Covid to save lives that have been lost daily since March and includes understanding application of things like VitD3, famotidine, invermectin, hcq/cq, etc.  Of that 4% of NIAID budget allocated for therapeutics, 75% of that went to Lilly’s monoclonal antibody. 

It's not that the there is no evidence favoring repurposed generics as the mountain of international studies demonstrate, it's that the NIAID decided at inception to bail on understanding the whole lot and going all in on vaccines.  Meanwhile 200k+ dead Americans and counting.

Also note HIV still receiving a whopping 35% of total NIAID funds, accounting for 0.3 deaths per Million US pop. by 2007.  

[Anastasis 23484]

I'd say that they made the right choice in terms of priorities. 10%, not 4%, went to therapeutics if you are comparing the proportion of COVID funds.

There does not appear to be a way out of this until we have a broad vaccination program. I don't really see a problem with a disproportionate focus on driving vaccine development and manufacture. They are trying to accelerate a process that typically takes many years into a time frame measured in months. No rational person wants to divert money from vaccine development to more HCQ trials or other very low effect size potential treatments.

Meanwhile, instead of more negative HCQ trials, PFE announces that they will likely be prepared for an EUA application in mid November.  This is absolutely unprecedented from a vaccine development process. 

 

https://www.statnews.com/2020/10/16/pfizer-wont-apply-for-covid19-vaccine-authorization-before-mid-november/

Bourla’s letter includes three new details:

— Pfizer and BioNTech will have two months of safety data on half the patients in their 44,000-patient vaccine study in the third week of November, based on current enrollment rates. This would allow the companies to file for an emergency use authorization.

— The independent data safety monitoring board, a panel of experts monitoring the study, will conduct interim analyses of the effectiveness of the vaccine. This is what originally drove the October timeline.

— Pfizer said that it “will share any conclusive readout” from these interim analyses, be they positive or negative, but that the study will continue until its conclusion.

[Hmbre97 6331]

17 hours ago, triplehorn said:

 

 

Also note HIV still receiving a whopping 35% of total NIAID funds, accounting for 0.3 deaths per Million US pop. by 2007.  

HIV/AIDS isn't just an issue in the US...

[jimmyjazz 46124]

37 minutes ago, Anastasis said:

There does not appear to be a way out of this until we have a broad vaccination program.

If an effective therapeutic were widely available at a reasonable cost, I'm not entirely sure I agree.  Imagine a treatment that virtually guarantees the course of the disease will be mild.  Combined with moderate ongoing immunity for a few months, covid could transform from a lethal pandemic to "shit, I'm down for 3-5 days once or twice a year", kinda like . . . the flu or a rhinovirus.

That said, we surely WILL have a reasonably effective vaccine, so the story tends to write itself, but for a variety of reasons, that's not likely to protect more than maybe half the population (70% efficacy for 70% of the population, which is of course a SWAG).

[Anastasis 23484]

5 minutes ago, jimmyjazz said:

If an effective therapeutic were widely available at a reasonable cost, I'm not entirely sure I agree.  Imagine a treatment that virtually guarantees the course of the disease will be mild.  Combined with moderate ongoing immunity for a few months, covid could transform from a lethal pandemic to "shit, I'm down for 3-5 days once or twice a year", kinda like . . . the flu or a rhinovirus.

Well sure if you make assumptions on the extreme end of potential effect size and cost, you can probably come up with a different conclusion.  Those assumptions however do not appear to have any basis in the reality of the therapeutics that have been evaluated against this viral disease.  Maybe the unicorn you describe exists in the wild and has been missed. It's quite possible.  OTOH, we have actually made meaningful effort towards standing up huge clinical trials and a manufacturing infrastructure in unprecedented time.  I think that the money was well spent and appropriately prioritized.  

[jimmyjazz 46124]

7 minutes ago, Anastasis said:

Well sure if you make assumptions on the extreme end of potential effect size and cost, you can probably come up with a different conclusion.  Those assumptions however do not appear to have any basis in the reality of the therapeutics that have been evaluated against this viral disease.  Maybe the unicorn you describe exists in the wild and has been missed. It's quite possible.  OTOH, we have actually made meaningful effort towards standing up huge clinical trials and a manufacturing infrastructure in unprecedented time.  I think that the money was well spent and appropriately prioritized.  

I am not aware if such a therapeutic would be a "unicorn".  Is Tamiflu effective at reducing the symptoms and duration of the flu?  Would such a thing be overly optimistic for covid?  (Just to be clear, I'm not suggesting the use of Tamiflu for covid.  I'm asking if a "Tamivid" could be found with more money thrown at the problem.)

Honest question.   This ain't my field.  I think my concern about the % of population who will willingly get a vaccine is well-founded.  Less than half of all Americans get the flu vaccine.  Maybe that number would be higher for a more serious disease.

[Horn Under a Bad Sign 20486]

 

[Bama Chick 28596]

BUT WE ARE RESPECTED ON THE WORLD STAGE AGAIN

[cactusflinthead 27601]

 

[BehoId, The Underminer! 11669]

I feels good to be respected as a country again.

 

 

 

 

[Anastasis 23484]

5 hours ago, jimmyjazz said:

I am not aware if such a therapeutic would be a "unicorn".  Is Tamiflu effective at reducing the symptoms and duration of the flu?  Would such a thing be overly optimistic for covid?  (Just to be clear, I'm not suggesting the use of Tamiflu for covid.  I'm asking if a "Tamivid" could be found with more money thrown at the problem.)

Any idea what Tamiflu costed when it was launched to market?  Not really an example that meets your two prongs.

 

Triple actually has a good point that in order to meet the requirements laid out you have to screen existing drugs for cross over effect on COVID.  There was a lot of effort put into HCQ exactly for that reason...low cost, oral administration, widely available, etc.  That's why a lot of people were optimistic when the initial dat, based largely on bad animal models circulated. Unfortunately it just didn't pan out. I do think other candidates deserve a fair shake.  But at this point we are very close to a vaccine EUA, and I think that complaining about the investment in that program is wrong headed. 

[jimmyjazz 46124]

47 minutes ago, Anastasis said:

Any idea what Tamiflu costed when it was launched to market?  

No idea.

 

Quote

Triple actually has a good point that in order to meet the requirements laid out you have to screen existing drugs for cross over effect on COVID.  There was a lot of effort put into HCQ exactly for that reason...low cost, oral administration, widely available, etc.  That's why a lot of people were optimistic when the initial dat, based largely on bad animal models circulated. Unfortunately it just didn't pan out. I do think other candidates deserve a fair shake.  But at this point we are very close to a vaccine EUA, and I think that complaining about the investment in that program is wrong headed. 

No doubt.  I wonder how much politics played into budgets, but I'll never know and it may be an unfounded concern.

Do you agree that there is some concern about vaccine penetration X efficacy?  What if in the end that's not enough to reach herd immunity?

[Bama Chick 28596]

Branded Tamiflu costs between $175-250 without insurance currently.

It was launched in 1999 and I couldn’t find anything on the Google about its launch price.