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CR: COVID-19 --Political Talk


Mrs Whiggins

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On 2/17/2021 at 8:21 PM, jimmyjazz said:

These tweets are really helpful, but it feels like they ignore the ~ 90M Americans who have already had the virus.  If that's as good as a vaccine, then we're probably closer to 7 months to herd immunity.

Or less...

 

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A WSJ OpEd from a surgeon and a medical professor and a medical advisor to a shady telemedicine company that targets the uninsured and a Fox New contributor, AND has been trotted out by Trump and Gingrich and The Heritage Foundation?

Excuse me if I’ll take his opinion with a big fucking grain of salt.

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1 hour ago, Bama Chick said:

A WSJ OpEd from a surgeon and a medical professor and a medical advisor to a shady telemedicine company that targets the uninsured and a Fox New contributor, AND has been trotted out by Trump and Gingrich and The Heritage Foundation?

Excuse me if I’ll take his opinion with a big fucking grain of salt.

His CV is pretty impressive, but it’s your right to dismiss his interpretation of the situation. I’m sorry he’s been “trotted out” by people or entities you dislike. 
 

2 hours ago, HenryJames said:

 

I can buy the argument that Dr Makary undersells the potential impact of variants.
 

But, I’m curious how he so easily dismissed the math that finds that 55% of Americans have natural immunity at this point. 

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April is too early. But I think we are largely opened up by July 4, herd immunity or not, barring any crazy shit. Some people will choose to play it more conservative, but most people that want vaccines will have them by that point and people will be ready to act like social animals again. 

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April is too early. But I think we are largely opened up by July 4, herd immunity or not, barring any crazy shit. Some people will choose to play it more conservative, but most people that want vaccines will have them by that point and people will be ready to act like social animals again. 
Agree, we will roll into summer turning the corner.
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58 minutes ago, fakebusiness said:

Can you still spread the virus if you're vaccinated?

According to this NYT article, chances are very low:

https://www.nytimes.com/2021/01/18/briefing/donald-trump-pardon-phil-spector-coronavirus-deaths.html?campaign_id=9&emc=edit_nn_20210218&instance_id=27279&nl=the-morning&regi_id=76257009&segment_id=51953&te=1&user_id=70324fd0ce2415cfbf9a7651cef607b8

An excerpt: Although no rigorous study has yet analyzed whether vaccinated people can spread the virus, it would be surprising if they did. “If there is an example of a vaccine in widespread clinical use that has this selective effect — prevents disease but not infection — I can’t think of one!” Dr. Paul Sax of Harvard has written in The New England Journal of Medicine. (And, no, exclamation points are not common in medical journals.) On Twitter, Dr. Monica Gandhi of the University of California, San Francisco, argued: “Please be assured that YOU ARE SAFE after vaccine from what matters — disease and spreading.”

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FL Gov Ron DeSantis is playing favorites with the coronavirus vaccine.

https://www.cbsnews.com/news/florida-governor-ron-desantis-covid-19-vaccine-distribution/

 

Quote

In Manatee County, Florida, this week, thousands of people got called to come to the affluent Lakewood Ranch development and get a coronavirus vaccine. It was a call many had been waiting for.

"We were very fortunate, we got the call, we came right down," one woman told CBS News' Jim Axelrod. 

It was more than good fortune. Those who received the call all lived in two specific zip codes. Their doses came through a deal struck by Florida's Republican Governor Ron DeSantis and the CEO of Lakewood Ranch's parent company, owned by major Republican donors.

Manatee County Commissioner Misty Servia said in a county meeting that the deal bypassed county protocol, allowing a select group of residents to go the front of the vaccine line.

"So rather than this randomized pool where everybody gets a fair shake, these two zip codes were going to receive preferential treatment," she said.

At a county meeting, Servia, who is also a Republican, told the room that the optics are horrible.

The zip codes are two of the county's wealthiest and whitest, and they're in the bottom half of COVID-19 rates countywide.

"It's just wrong. I mean, that's the bottom line," said Patrick Carnegie said, who runs MCR Health, the region's largest primary care provider, which has been assisting in administrating COVID-19 vaccines.

"We want to make sure that the process is done fair, and it's done, you know, equitably across the board," he said. 

According to Florida state guidance, long-term care facility residents and staff, healthcare workers in direct contact with COVID-19 patients, including paramedics and EMS, and people age 65 and older are eligible to get vaccinated.  

DeSantis said on Wednesday he was trying to get the vaccine to a high concentration of seniors. But in a county full of seniors, he never explained why the doses were limited to just this group. He threatened to take the shots elsewhere.

"If Manatee County doesn't like us doing this, then we are totally fine with putting this in counties that want it. We're totally happy to do that," DeSantis said.

The governor is also under scrutiny for selecting the supermarket chain, Publix, to be the sole distributor of vaccines in a handful of Florida counties following a $100,000 donation the company made to DeSantis' reelection PAC. 

Servia is now facing criticism from her own party, saying she should be "ashamed" that she "took a page out of the Biden playbook in attacking Florida and ... Governor DeSantis."

 

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UK took a lot of shit for extending the dosing interval to accelerate first dose administration.  Turns out they were right to do so, and the result was greater effectiveness.

http://www.thelancet-press.com/embargo/oxfordvaccineinterval.pdf?

Findings Between April 23 and Dec 6, 2020, 24422 participants were recruited and vaccinated across the four studies, of whom 17178 were included in the primary analysis (8597 receiving ChAdOx1 nCoV-19 and 8581 receiving control vaccine). The data cutoff for these analyses was Dec 7, 2020. 332 NAAT-positive infections met the primary endpoint of symptomatic infection more than 14 days after the second dose. Overall vaccine efficacy more than 14 days after the second dose was 66·7% (95% CI 57·4–74·0), with 84 (1·0%) cases in the 8597 participants in the ChAdOx1 nCoV-19 group and 248 (2·9%) in the 8581 participants in the control group. There were no hospital admissions for COVID-19 in the ChAdOx1 nCoV-19 group after the initial 21-day exclusion period, and 15 in the control group. 108 (0·9%) of 12282 participants in the ChAdOx1 nCoV-19 group and 127 (1·1%) of 11962 participants in the control group had serious adverse events. There were seven deaths considered unrelated to vaccination (two in the ChAdOx1 nCov-19 group and five in the control group), including one COVID-19-related death in one participant in the control group. Exploratory analyses showed that vaccine efficacy after a single standard dose of vaccine from day 22 to day 90 after vaccination was 76·0% (59·3–85·9). Our modelling analysis indicated that protection did not wane during this initial 3-month period. Similarly, antibody levels were maintained during this period with minimal waning by day 90 (geometric mean ratio [GMR] 0·66 [95% CI 0·59–0·74]). In the participants who received two standard doses, after the second dose, efficacy was higher in those with a longer prime-boost interval (vaccine efficacy 81·3% [95% CI 60·3–91·2] at ≥12 weeks) than in those with a short interval (vaccine efficacy 55·1% [33·0–69·9] at <6 weeks). These observations are supported by immunogenicity data that showed binding antibody responses more than two-fold higher after an interval of 12 or more weeks compared with an interval of less than 6 weeks in those who were aged 18–55 years (GMR 2·32 [2·01–2·68]).

Interpretation The results of this primary analysis of two doses of ChAdOx1 nCoV-19 were consistent with those seen in the interim analysis of the trials and confirm that the vaccine is efficacious, with results varying by dose interval in exploratory analyses. A 3-month dose interval might have advantages over a programme with a short dose interval for roll-out of a pandemic vaccine to protect the largest number of individuals in the population as early as possible when supplies are scarce, while also improving protection after receiving a second dose.

 

Edited by Anastasis
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FL Gov Ron DeSantis is playing favorites with the coronavirus vaccine.
https://www.cbsnews.com/news/florida-governor-ron-desantis-covid-19-vaccine-distribution/
 
In Manatee County, Florida, this week, thousands of people got called to come to the affluent Lakewood Ranch development and get a coronavirus vaccine. It was a call many had been waiting for.
"We were very fortunate, we got the call, we came right down," one woman told CBS News' Jim Axelrod. 
It was more than good fortune. Those who received the call all lived in two specific zip codes. Their doses came through a deal struck by Florida's Republican Governor Ron DeSantis and the CEO of Lakewood Ranch's parent company, owned by major Republican donors.
Manatee County Commissioner Misty Servia said in a county meeting that the deal bypassed county protocol, allowing a select group of residents to go the front of the vaccine line.
"So rather than this randomized pool where everybody gets a fair shake, these two zip codes were going to receive preferential treatment," she said.
At a county meeting, Servia, who is also a Republican, told the room that the optics are horrible.
The zip codes are two of the county's wealthiest and whitest, and they're in the bottom half of COVID-19 rates countywide.
"It's just wrong. I mean, that's the bottom line," said Patrick Carnegie said, who runs MCR Health, the region's largest primary care provider, which has been assisting in administrating COVID-19 vaccines.
"We want to make sure that the process is done fair, and it's done, you know, equitably across the board," he said. 
According to Florida state guidance, long-term care facility residents and staff, healthcare workers in direct contact with COVID-19 patients, including paramedics and EMS, and people age 65 and older are eligible to get vaccinated.  
DeSantis said on Wednesday he was trying to get the vaccine to a high concentration of seniors. But in a county full of seniors, he never explained why the doses were limited to just this group. He threatened to take the shots elsewhere.
"If Manatee County doesn't like us doing this, then we are totally fine with putting this in counties that want it. We're totally happy to do that," DeSantis said.
The governor is also under scrutiny for selecting the supermarket chain, Publix, to be the sole distributor of vaccines in a handful of Florida counties following a $100,000 donation the company made to DeSantis' reelection PAC. 
Servia is now facing criticism from her own party, saying she should be "ashamed" that she "took a page out of the Biden playbook in attacking Florida and ... Governor DeSantis."
 
@MNLonghornFUKM this is a "wait and see" for me. Smoke for sure, but can't tell if there's a fire yet. Looks sketchy, but I can only find one article about it so far. Withholding judgement.
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Someone please tell me not to believe this article...can't take much more doom and gloom.

https://www.msn.com/en-us/news/world/covid-19-variant-found-in-uk-spreads-like-wildfire-british-experts-fear-what-will-happen-if-us-won-t-lock-down/ar-BB1dPZgc

excerpts:

Simon Clarke, a professor in cellular microbiology at the University of Reading, said there is an emerging body of evidence suggesting that the B.1.1.7 variant is not only more contagious but also more lethal, a possibility initially raised by British scientists. He said there is anecdotal evidence from hospitals, not confirmed by studies, that the B.1.1.7 variant could harm more younger people. He cautioned it was too early to drawn firm conclusions. 

He expressed concern about how the United States would deal with B.1.1.7 if, as expected,it becomes entrenched as the dominant variant by the spring. 

"U.S. coronavirus waves have been based on slower-moving variants," Clarke said. 

"If a faster-moving one such as B.1.1.7 starts to take off, then you are going to have yourself a problem if you're not prepared to do a strict, broad-based national lockdown," Clarke said, noting that the United States doesn't seem willing to do this. 

...

Pagel cautioned that if the variant first detected in Britain is allowed to circulate too freely in the USA, it could lead to an even more aggressive variation that could evade vaccines or better target younger people.

She said that  cases of an older variant could fall  rapidly enough that it might look like everything was OK even while a new variant spread.

"Effectively, you have two epidemics going on at the same time where one is shrinking, and one is growing," she said. "That's exactly what happened in the U.K. and seems likely for the U.S."

 

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Someone please tell me not to believe this article...can't take much more doom and gloom.
https://www.msn.com/en-us/news/world/covid-19-variant-found-in-uk-spreads-like-wildfire-british-experts-fear-what-will-happen-if-us-won-t-lock-down/ar-BB1dPZgc
excerpts:

Simon Clarke, a professor in cellular microbiology at the University of Reading, said there is an emerging body of evidence suggesting that the B.1.1.7 variant is not only more contagious but also more lethal, a possibility initially raised by British scientists. He said there is anecdotal evidence from hospitals, not confirmed by studies, that the B.1.1.7 variant could harm more younger people. He cautioned it was too early to drawn firm conclusions. 

He expressed concern about how the United States would deal with B.1.1.7 if, as expected,it becomes entrenched as the dominant variant by the spring. 

"U.S. coronavirus waves have been based on slower-moving variants," Clarke said. 

"If a faster-moving one such as B.1.1.7 starts to take off, then you are going to have yourself a problem if you're not prepared to do a strict, broad-based national lockdown," Clarke said, noting that the United States doesn't seem willing to do this. 

...

Pagel cautioned that if the variant first detected in Britain is allowed to circulate too freely in the USA, it could lead to an even more aggressive variation that could evade vaccines or better target younger people.

She said that  cases of an older variant could fall  rapidly enough that it might look like everything was OK even while a new variant spread.

"Effectively, you have two epidemics going on at the same time where one is shrinking, and one is growing," she said. "That's exactly what happened in the U.K. and seems likely for the U.S."

 

Get vaccines in arms.

That information has been reported previously and discussed in this thread.
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1 hour ago, DDD Dad said:


Get vaccines in arms.

That information has been reported previously and discussed in this thread.

I don't know if people are going to continue to follow edicts delivered by a man w/no college degree or medical experience that wants to globally privatize healthcare. 

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Maybe I’m being way too naive, but it seems to me like the UK variant, while a concern, shouldn’t be that frightening. If we only continue vaccinating 1.5 million people per day and you assume that actual daily cases is say 5x of confirmed cases, we’re outpacing the virus by over a million potential hosts per day. Like I said, maybe I’m just being stupid here, but as long as the vaccine program continues ramping up, I don’t see another huge spike coming unless the variant re-infects previous cases. 

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15 hours ago, ChuckNorrisActionJeans said:

Someone please tell me not to believe this article...can't take much more doom and gloom.

https://www.msn.com/en-us/news/world/covid-19-variant-found-in-uk-spreads-like-wildfire-british-experts-fear-what-will-happen-if-us-won-t-lock-down/ar-BB1dPZgc

excerpts:

Simon Clarke, a professor in cellular microbiology at the University of Reading, said there is an emerging body of evidence suggesting that the B.1.1.7 variant is not only more contagious but also more lethal, a possibility initially raised by British scientists. He said there is anecdotal evidence from hospitals, not confirmed by studies, that the B.1.1.7 variant could harm more younger people. He cautioned it was too early to drawn firm conclusions. 

He expressed concern about how the United States would deal with B.1.1.7 if, as expected,it becomes entrenched as the dominant variant by the spring. 

"U.S. coronavirus waves have been based on slower-moving variants," Clarke said. 

"If a faster-moving one such as B.1.1.7 starts to take off, then you are going to have yourself a problem if you're not prepared to do a strict, broad-based national lockdown," Clarke said, noting that the United States doesn't seem willing to do this. 

...

Pagel cautioned that if the variant first detected in Britain is allowed to circulate too freely in the USA, it could lead to an even more aggressive variation that could evade vaccines or better target younger people.

She said that  cases of an older variant could fall  rapidly enough that it might look like everything was OK even while a new variant spread.

"Effectively, you have two epidemics going on at the same time where one is shrinking, and one is growing," she said. "That's exactly what happened in the U.K. and seems likely for the U.S."

 

 

image.png.e7f84c6dd9e11ee314bd811f70f28a5e.png

image.png.097321182d484b634fba348afd4bdca3.png

 

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