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CR: COVID-19 --Political Talk

Mrs Whiggins

By Mrs Whiggins
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I'd just like to point out that neither myself nor any of my fellow nurses, fellow advanced nurse practitioners, and other healthcare providers ever swore an oath that we would lay down our lives for

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Welp, it finally happened. I snapped in public today. I went into work for a bit this morning because I’m trying to figure out the safest way to host physicians we are recruiting given our CV-19 sit

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I don't really know what to say anymore tbh. What happened last night is hard to put into words for anyone who hasn't worked in a hospital healthcare setting. Just unreal. Everyone is getting fucked.

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aggie08

aggie08 21504

Posted
Posted (edited)
24 minutes ago, Incredulity said:

Utterly in awe of the fart sniffing sophistication of Surly leftists.

 

You cracked the code Sherlock 

Being able to determine that vaccines = good on our own is considered fart sniffing sophistication, huh?

Cool. I'm sophisticated af.

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PsychMike

PsychMike 1552

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Posted
On 9/14/2021 at 8:35 AM, PassiveAggressiveCoach said:

LOL, OK or he was caught off guard and knows the data is showing natural immunity is much better than vax immunity but didn't want to undermine the Biden draconian mandate. 

Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients

Affiliations collapse

Affiliations

  • 1Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece. itrougakos@biol.uoa.gr.
  • 2Department of Clinical Therapeutics, School of Medicine, Alexandra General Hospital, National and Kapodistrian University of Athens, Athens, Greece. eterpos@med.uoa.gr.
  • 3Thoracic Diseases General Hospital Sotiria, Athens, Greece.
  • 4Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
  • 5Department of Clinical Biochemistry, "Aghia Sophia" Children's Hospital, Athens, Greece.
  • 6Department of Clinical Therapeutics, School of Medicine, Alexandra General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • 7Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
#Contributed equally.
Free PMC article

Abstract

Background: Coronavirus SARS-CoV-2, the causative agent of COVID-19, has caused a still evolving global pandemic. Given the worldwide vaccination campaign, the understanding of the vaccine-induced versus COVID-19-induced immunity will contribute to adjusting vaccine dosing strategies and speeding-up vaccination efforts.

Methods: Anti-spike-RBD IgGs and neutralizing antibodies (NAbs) titers were measured in BNT162b2 mRNA vaccinated participants (n = 250); we also investigated humoral and cellular immune responses in vaccinated individuals (n = 21) of this cohort 5 months post-vaccination and assayed NAbs levels in COVID-19 hospitalized patients (n = 60) with moderate or severe disease, as well as in COVID-19 recovered patients (n = 34).

Results: We found that one (boosting) dose of the BNT162b2 vaccine triggers robust immune (i.e., anti-spike-RBD IgGs and NAbs) responses in COVID-19 convalescent healthy recipients, while naïve recipients require both priming and boosting shots to acquire high antibody titers. Severe COVID-19 triggers an earlier and more intense (versus moderate disease) immune response in hospitalized patients; in all cases, however, antibody titers remain at high levels in COVID-19 recovered patients. Although virus infection promotes an earlier and more intense, versus priming vaccination, immune response, boosting vaccination induces antibody titers significantly higher and likely more durable versus COVID-19. In support, high anti-spike-RBD IgGs/NAbs titers along with spike (vaccine encoded antigen) specific T cell clones were found in the serum and peripheral blood mononuclear cells, respectively, of vaccinated individuals 5 months post-vaccination.

Conclusions: These findings support vaccination efficacy, also suggesting that vaccination likely offers more protection than natural infection.

Keywords: Anti-S-RBD IgGs; BNT162b2 vaccine; COVID-19; Neutralizing antibodies; SARS-CoV-2; Viral infection.

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Genco

Genco 3041

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Posted
14 minutes ago, PsychMike said:

Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients

Affiliations collapse

Affiliations

  • 1Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece. itrougakos@biol.uoa.gr.
  • 2Department of Clinical Therapeutics, School of Medicine, Alexandra General Hospital, National and Kapodistrian University of Athens, Athens, Greece. eterpos@med.uoa.gr.
  • 3Thoracic Diseases General Hospital Sotiria, Athens, Greece.
  • 4Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
  • 5Department of Clinical Biochemistry, "Aghia Sophia" Children's Hospital, Athens, Greece.
  • 6Department of Clinical Therapeutics, School of Medicine, Alexandra General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
  • 7Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
#Contributed equally.

Free PMC article

Abstract

Background: Coronavirus SARS-CoV-2, the causative agent of COVID-19, has caused a still evolving global pandemic. Given the worldwide vaccination campaign, the understanding of the vaccine-induced versus COVID-19-induced immunity will contribute to adjusting vaccine dosing strategies and speeding-up vaccination efforts.

Methods: Anti-spike-RBD IgGs and neutralizing antibodies (NAbs) titers were measured in BNT162b2 mRNA vaccinated participants (n = 250); we also investigated humoral and cellular immune responses in vaccinated individuals (n = 21) of this cohort 5 months post-vaccination and assayed NAbs levels in COVID-19 hospitalized patients (n = 60) with moderate or severe disease, as well as in COVID-19 recovered patients (n = 34).

Results: We found that one (boosting) dose of the BNT162b2 vaccine triggers robust immune (i.e., anti-spike-RBD IgGs and NAbs) responses in COVID-19 convalescent healthy recipients, while naïve recipients require both priming and boosting shots to acquire high antibody titers. Severe COVID-19 triggers an earlier and more intense (versus moderate disease) immune response in hospitalized patients; in all cases, however, antibody titers remain at high levels in COVID-19 recovered patients. Although virus infection promotes an earlier and more intense, versus priming vaccination, immune response, boosting vaccination induces antibody titers significantly higher and likely more durable versus COVID-19. In support, high anti-spike-RBD IgGs/NAbs titers along with spike (vaccine encoded antigen) specific T cell clones were found in the serum and peripheral blood mononuclear cells, respectively, of vaccinated individuals 5 months post-vaccination.

Conclusions: These findings support vaccination efficacy, also suggesting that vaccination likely offers more protection than natural infection.

Keywords: Anti-S-RBD IgGs; BNT162b2 vaccine; COVID-19; Neutralizing antibodies; SARS-CoV-2; Viral infection.

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Sawbonz

Sawbonz 27565

Posted
Posted
5 hours ago, Horn Dog said:

It is an amazing timeline.  That friend of a cousin of Minaj went out and got VD, blamed the vax, and 35% of our country completely buys it.   If you have a trump loving spouse/partner right now, there is a very high chance you could get caught  with your dick in someone else and you could blame the vax and it would make perfect sense to them.

 

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Horn Under a Bad Sign

Horn Under a Bad Sign 20402

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So some comedian named Jim Breuer was apparently on Tucker Carlson and said he's not going to perform at any venue that requires vaccination.  I've never heard of the guy but doesn't that mean that he's basically going to be performing at truck stops in Amarillo and Braum's Ice Cream shop in Anadarko? Bonus for Tucker's expression during this spiel.

 


 

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cactusflinthead

cactusflinthead 27598

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Posted
10 hours ago, Incredulity said:

Leftist bitches whining about neg rep will never not be funny 

What does it say about you then? You made sure to return the negs. You earned every one of them. But, in return picked rando comments of your targets.

At the very least I have inflammatory comments right here in this thread. Did it make you feel funny to neg Kenneth?

It's ok. He won't mind. He'll never know.

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GopherRock

GopherRock 1765

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Posted
15 hours ago, Horn Dog said:

It is an amazing timeline.  That friend of a cousin of Minaj went out and got VD, blamed the vax, and 35% of our country completely buys it.   If you have a trump loving spouse/partner right now, there is a very high chance you could get caught  with your dick in someone else and you could blame the vax and it would make perfect sense to them.

 

 

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Sawbonz

Sawbonz 27565

Posted
Posted
1 hour ago, Captainant said:

Another success story for @Satoshi - he wants more people to die like this

Odds are that dude had not had covid already. One super nutter who is the older brother of guys I grew up with rants constantly about chin diapers and kids getting CO2 poisoning and “the jab” being worthless. He posted the other day that he’s had covid twice and did just fine. I wanted so bad to post bitch you don’t even believe the virus is real and you want us to believe you went and got a covid test not once but twice?

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Satoshi

Satoshi 129

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Posted
1 hour ago, Captainant said:

Another success story for @Satoshi - he wants more people to die like this

Is this some kind of gotcha? I never said you couldn’t die after you’ve had covid. I said that natural immunity is roughly equivalent to vaccine immunity. In the same way that a breakthrough infection can kill someone, so too can a re-infection. But these are quite rare. 
 

8 minutes ago, Sawbonz said:

Odds are that dude had not had covid already. One super nutter who is the older brother of guys I grew up with rants constantly about chin diapers and kids getting CO2 poisoning and “the jab” being worthless. He posted the other day that he’s had covid twice and did just fine. I wanted so bad to post bitch you don’t even believe the virus is real and you want us to believe you went and got a covid test not once but twice?

You may be on to something here. 

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