Fentanyl laced Oxy, Valium, and Xanax

[Captainant 27625]

1 minute ago, High Plains Drifter said:

is weed ever laced with fentanyl? If so, is smoking fentanyl as bad as ingesting? 

This is the biggest concern I have with the stupid delta8 and whole rainbow of synthetic weeds - it makes the opening for contaminants to get on, where a well regulated weed industry with lab testing wouldn't have those problems. 

[Bevo 13560]

2 minutes ago, High Plains Drifter said:

 

 

OK, so asking for all those weed smoking teens...

 

is weed ever laced with fentanyl? If so, is smoking fentanyl as bad as ingesting? 

 

 

Yes, but compared to injecting heroin, there is a tradeoff. You don't have the extra danger of infected needles.

[We’reTexas 1473]

1 hour ago, Homercles said:

Guess I don’t understand where any confusion comes from…stuff is so powerful that a few grains are enough to kill a person = much easier to smuggle weight = cheap way to offset your shitty/weaker actual drugs = gets used in just about anything.  

Doubt there’s anyone out there who seeks it like they did oxy…in fact they make test kits so you can avoid it…because the margin of error is so minuscule that a tiny difference in how well it’s measured/mixed leads to vast variability in fentanyl per dose of adulterated h/coke/pills/x.  

The pill press in your warehouse ends up with a chunk smaller than a grain of salt stuck to it, passed onto one fake Xanax by accident?  Deadly.  

Yep, it’s just supply and demand. Crackdown on prescription opioids sent prices up and people to heroin, crackdown on heroin sent prices up and dealers cutting with fentanyl. At this point in the crisis addicts buy it as a standalone product. 

[Brian Fantana 6678]

5 hours ago, We’reTexas said:

Yep, it’s just supply and demand. Crackdown on prescription opioids sent prices up and people to heroin, crackdown on heroin sent prices up and dealers cutting with fentanyl. At this point in the crisis addicts buy it as a standalone product. 

Let's not fail to mention the loss of supply from Afghanistan. That is more or less a permanent crater in the world's opium supply.

e: Maybe not permanent

Edited March 6 by Brian Fantana

[MrBig 5370]

6 hours ago, Homercles said:

Guess I don’t understand where any confusion comes from…stuff is so powerful that a few grains are enough to kill a person = much easier to smuggle weight = cheap way to offset your shitty/weaker actual drugs = gets used in just about anything.  

Doubt there’s anyone out there who seeks it like they did oxy…in fact they make test kits so you can avoid it…because the margin of error is so minuscule that a tiny difference in how well it’s measured/mixed leads to vast variability in fentanyl per dose of adulterated h/coke/pills/x.  

The pill press in your warehouse ends up with a chunk smaller than a grain of salt stuck to it, passed onto one fake Xanax by accident?  Deadly.  

People who make fake Xanax cut their product with fentanyl to make it effective. This means adding a scoop of fentanyl into a jar with the rest of the product and mixing it around to make sure the fentanyl gets mixed in.

The problem is that the jar is just mixed without any way to test how the fentanyl is distributed throughout the product.

So some people in that batch might get a shitload of fentanyl in their pills while others are getting weak shit from the same batch. This is why people die.

[Nicole44 22057]

The Storage Wars episode would have been classic: reminder to myself to pick up more food storage containers.

 

 

[Brisketexan 105057]

On 3/5/2024 at 2:52 PM, High Plains Drifter said:

 

 

OK, so asking for all those weed smoking teens...

 

is weed ever laced with fentanyl? If so, is smoking fentanyl as bad as ingesting? 

 

 

I understand (but I admit to not having all the details, nor was I ever going to ask) that the child of some folks I know died from just such a circumstance (smoked some weed that somehow was tainted with fentanyl).  Some discussion of whether it was laced, or just cross-contaminated.  So, don't know how big of a risk it really is.

BTW, a year ago, I had a surgical procedure, and when I came out, I had a HELLACIOUS post-anesthesia headache.  Debilitating.  They gave me a dose of fentanyl.  It might as well have been a tic-tac.  Vicodin has worked for me in the past, Fentanyl did nothing.

[Brian Fantana 6678]

On 3/5/2024 at 9:13 PM, MrBig said:

People who make fake Xanax cut their product with fentanyl to make it effective. This means adding a scoop of fentanyl into a jar with the rest of the product and mixing it around to make sure the fentanyl gets mixed in.

The problem is that the jar is just mixed without any way to test how the fentanyl is distributed throughout the product.

So some people in that batch might get a shitload of fentanyl in their pills while others are getting weak shit from the same batch. This is why people die.

Not gonna lie the way you worded this sounds completely made up (not saying you did but lol)

[MrBig 5370]

11 hours ago, Brian Fantana said:

Not gonna lie the way you worded this sounds completely made up (not saying you did but lol)

 

[Captainant 27625]

Some rare positive news in this area - UH is about to start clinical trials on a vaccine for fentanyl 

https://www.statesman.com/story/news/state/2024/09/06/fentanyl-vaccine-university-of-houston-texas-opioid-crisis/75085964007/

From the article:

UH psychology and addictions researcher Colin Haile said clinical trials for a fentanyl vaccine would start next year. He noted that vaccines train the immune system to identify the opioid and block it from reaching the brain.

"In a prototypical vaccine, you’re vaccinated with a piece of bacteria or virus you want to be protected against,” Haile told UH Magazine. “Your body recognizes it as foreign, then develops antibodies against that pathogen. What we’ve done here is (produced) a vaccine that (creates) antibodies against a chemical: fentanyl. We vaccinate, and the individual develops anti-fentanyl antibodies, which bind to the chemical and prevent it from getting to the brain, instead keeping it in the blood until it is eventually eliminated from the body.”

[drt 638]

What’s the use case for that? Give it to every kid just in case? Or would the plan be for folks who plan to have risky behaviors seek out the vaccine, basically meaning they don’t have to carry narcan

[We’reTexas 1473]

What’s the use case for that? Give it to every kid just in case? Or would the plan be for folks who plan to have risky behaviors seek out the vaccine, basically meaning they don’t have to carry narcan

Hand it out in downtown San Francisco and other open air drug markets throughout the country. The overdose problem has been insane.

[Captainant 27625]

1 hour ago, drt said:

What’s the use case for that? Give it to every kid just in case? Or would the plan be for folks who plan to have risky behaviors seek out the vaccine, basically meaning they don’t have to carry narcan

That and first responders, who frequently have to navigate that risk when responding to OD calls. I do wonder the feasibility of a vaccine to train your body to reject a molecule... If you could prevent an addicts brain from absorbing the opiate in the first place, it could really help to avoid a relapse and/or an OD. 

Edited September 17 by Captainant

[Herbie Hancock 7343]

It’s not discriminatory, so I’m curious how that works if you have this “vaccine” and are then involved in a traumatic event and need pain medications.


Also, the only risk to first responders on fentanyl related calls is the junkie waking up madder than shit, or pushing too much narcan and having them puke all over you and your ambulance.

[Deej 76752]

7 hours ago, drt said:

What’s the use case for that?

Just trying to get that new 6G chip into circulation. Duh.

[TexasEd 8066]

15 hours ago, Captainant said:

Some rare positive news in this area - UH is about to start clinical trials on a vaccine for fentanyl 

https://www.statesman.com/story/news/state/2024/09/06/fentanyl-vaccine-university-of-houston-texas-opioid-crisis/75085964007/

From the article:

UH psychology and addictions researcher Colin Haile said clinical trials for a fentanyl vaccine would start next year. He noted that vaccines train the immune system to identify the opioid and block it from reaching the brain.

"In a prototypical vaccine, you’re vaccinated with a piece of bacteria or virus you want to be protected against,” Haile told UH Magazine. “Your body recognizes it as foreign, then develops antibodies against that pathogen. What we’ve done here is (produced) a vaccine that (creates) antibodies against a chemical: fentanyl. We vaccinate, and the individual develops anti-fentanyl antibodies, which bind to the chemical and prevent it from getting to the brain, instead keeping it in the blood until it is eventually eliminated from the body.”

Yeah, why not alcohol or other drugs that have been around first?  Is there something about Fentanyl that lends itself to this vaccine defense that alcohol, heroine or meth doesn't? Or is Fentanyl just in the news enough to get the research funding?

[Bevo 13560]

23 minutes ago, TexasEd said:

Yeah, why not alcohol or other drugs that have been around first?  Is there something about Fentanyl that lends itself to this vaccine defense that alcohol, heroine or meth doesn't? Or is Fentanyl just in the news enough to get the research funding?

Ethanol would be a problem because it is endogenous as are other alcohols that include C2H6O . The other drugs would be fine to create antibodies against. It is not a great idea though.

[Herbie Hancock 7343]

Ethanol would be a problem because it is endogenous as are other alcohols that include C2H6O . The other drugs would be fine to create antibodies against. It is not a great idea though.

I could go for a CH4 vaccine for taco Tuesday at work.

[Bevo 13560]

39 minutes ago, Herbie Hancock said:

I could go for a CH4 vaccine for taco Tuesday at work.

 

 

Not  to ruin your joke, but I think the smallest epitope recognized by an antibody is about 3 amino acids - one that I'm aware of is Histidine - Histidine - Histidine.

[Herbie Hancock 7343]

 
 
Not  to ruin your joke, but I think the smallest epitope recognized by an antibody is about 3 amino acids - one that I'm aware of is Histidine - Histidine - Histidine.

[High Plains Drifter 11026]

8 hours ago, Bevo said:

 

 

Not  to ruin your joke, but I think the smallest epitope recognized by an antibody is about 3 amino acids - one that I'm aware of is Histidine - Histidine - Histidine.

 

I dated a Delta-Delta-Delta in college. Is that the same thing? If so this hits close to home about 40 years ago. 

 

 

Edited September 18 by High Plains Drifter
gramma

[Surly Bevo 24908]

So what happens when you have taken the fentanyl vaccine and you end up needing fentanyl in a clinical setting?

[Anastasis 23458]

57 minutes ago, Surly Bevo said:

So what happens when you have taken the fentanyl vaccine and you end up needing fentanyl in a clinical setting?

Shouldn’t affect other opiates, so there would still be options like morphine.