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Polio cases in Africa linked to new oral vaccine


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https://www.science.org/content/article/first-polio-cases-linked-new-oral-vaccine-detected-africa?utm_source=join1440&utm_medium=email&utm_placement=newsletter

A new oral vaccine "spreads itself."  Seems the weakened virus is a bit too hot and folks are getting full-blown Polio.  

Let's not let this thread go CR thx.

Cheap and easy to use, Albert Sabin’s OPV is hands down the best vaccine for eliminating polio in poor settings where clean water and sanitation are lacking. Children shed the weakened virus from the vaccine in their stool for a short time after they receive the oral drops, conferring immunity even on those who are not vaccinated. The problem is that in areas where polio vaccination rates are low, in rare cases the vaccine virus can continue to spread among un- or underimmunized people for months, accumulating enough mutations to revert to its paralytic form. This happens most often with poliovirus type 2, one of three serotypes. For years now, GPEI has been chasing its tail, quashing one type 2 outbreak with mOPV2 only to seed new outbreaks.

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Been hearing about this for awhile. I wonder if it's still a net positive or they just need to scrap it and go back to the drawing board. 

Crazy that there's places still fighting polio in 2023. Makes you appreciative of the developed world's ability to eradicate it. 

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23 hours ago, ztejas said:

Been hearing about this for awhile. I wonder if it's still a net positive or they just need to scrap it and go back to the drawing board. 

Crazy that there's places still fighting polio in 2023. Makes you appreciative of the developed world's ability to eradicate it. 

It sounds like a net positive overall. Not ideal, but I'm not sure any solution designed for impoverished areas is going to be ideal. Hopefully some sort of modification is possible that will lessen the chance of mutation back to its paralytic state while maintaining efficacy. 

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On 3/22/2023 at 8:30 AM, Dahobbs said:

It sounds like a net positive overall. Not ideal, but I'm not sure any solution designed for impoverished areas is going to be ideal. Hopefully some sort of modification is possible that will lessen the chance of mutation back to its paralytic state while maintaining efficacy. 

A quick google check shows the oral one isn’t approved for use in the US, which has used the very effective shot version since 2000.  Given it’s cheaper and requires fewer doses, makes sense it’s used in more impoverished regions.  

Key issue seems to be when it gets to spread in under-immunized populations, like that area of NY, and gets to mutate…that’s when it’s a net negative.  Of course it wouldn’t be a larger scale issue if those folks woulda gotten the right, needle-delivered vaccine and it never spreads in the first place.  

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On 3/21/2023 at 9:13 AM, Homercles said:

Well was being eradicated in the states until the latest rounds of Karen’s opposing it 

You’re going to need to translate “Karen” into a bunch of different languages bc the traditional vaccine preventable outbreaks are largely located in pockets of immigrant communities and in the far right Annnd far left enclaves as well. Vaccine stupidity does not discriminate.

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On 3/25/2023 at 7:53 AM, Texzilla58 said:

It’s a CR situation, we’ll documented as to the person pushing this new vaccine. The old vax practically eliminated the disease globally and here comes this new one and it back. Thanks Big Pharma!

no CR, but capitalism completely breaks down when industry is, for all intents & purposes, selling consumers their life or quality of life.  Leaving the public good to be safe guarded by the ethics and morality of capitalists is not working.

Ok, maybe a little CR.

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34 minutes ago, The Royal We said:

Yea, the guy trying to eradicate Malaria without using mass vaccinations is trying to depopulate the planet.

No! It makes perfect sense.

I mean, if you want to depopulate the planet, you have to eradicate polio by vaccinating the countries where it remains most prevalent, even though the birth rates in those countries has not shown a *marked drop-off and the number of polio cases is still <800 per 600 million doses administered (per the article) The 5th richest fella in the world is attempting to prove that he, too, makes bad and inefficient business decisions like the 2nd richest fella in the world, Elon Musk. Bill Gates is doing a remarkable job of depopulation per **ElonMetrics. Do the research man!

 

 

*Birth rates for the continent of Africa have shown a ~1% decrease, a combination of factors being: war, economic instability, pandemic, food insecurity, etc.

 

**patent pending on the brand.

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